CAS 28981-97-7

Alprazolam, is an natural compound with the components C17H13ClN4, commonly used for the cure of anxiety, depression, insomnia, can be used as an anti-panic drug, however additionally can relieve acute alcohol withdrawal symptoms, can additionally have a true therapeutic impact on drug-induced intractable hiccups.

Pharmacological action

This product is a new BDZ category drug, with comparable pharmacological outcomes as diazepam, with anxiolytic, antidepressant, sedative, hypnotic, anticonvulsant and muscle relaxant effects. Its anxiolytic impact is 10 instances superior than diazepam, and the mechanism of motion might also be associated to β-adrenergic receptors in the brain. The oral absorption of this product is fast and complete, and the top plasma awareness can be reached in 1 to two hours, the plasma half-life is 12 to 18 hours, and the plasma attention reaches a constant country in two to three days. Plasma protein binding is about 80%. After absorption, it is allotted all through the physique and can penetrate the placental barrier, and there are capsules in the milk. It was once metabolized by way of the liver CYP3A enzyme device to the lively substance α-hydroxytriazole, however the awareness was once too low and had no scientific significance. Finally, it is excreted from the kidneys, the accumulation in the physique is very small, and it is rapidly eliminated after stopping the drug.

Indications

1. For the cure of anxiety, despair and insomnia. Can be used as an anti-panic drug.

2. It can relieve acute alcohol withdrawal symptoms.

3. It has a properly therapeutic impact on drug-induced refractory hiccups.

Usage and dosage

Due to the one-of-a-kind dosage types and specifications, please study the drug guidelines cautiously or comply with the doctor's recommendation for dosage.