CAS 86393-34-2
2,4-DICHLORO-5-FLUOROBENZOYL CHLORIDE
2,4-Dichloro-5-Fluorosbenzoylchloride
2,4-difluoro-5-fluorobenzoyl chloride
2,4-DICHLORO-5-FLUOROBENZOYL CHLORIDE, 9 6%
2,4-Dichloro-5-fluorobenzoyl chloride 98%
2,4-Dichloro-5-fluorobenzoylchloride98%
5-FLUORO2,4-DICHLOROBENZOYLCHLORIDE
2,4-Dichlor-5-fluor-benzoylchlorid
Boiling Point: 143-144 °C35 mm Hg(lit.)
Density: 1.568 g/mL at 25 °C(lit.)
Refractive index n20/D 1.572(lit.)
Flash point > 230 °F
Specific gravity 1.568
Sensitivity: Moisture sensitivity
BRN4989077
CAS DataBase Reference: 86393-34-2
use
2,4-Dichloro-5-fluorobenzoyl chloride is the main raw material for the preparation of third-generation quinolones such as trifluoroperidinol, trifluoroguabutenyl, pentafluridol and synthetic broad-spectrum antibiotics such as ciprofloxacin, and can also be used for pesticides, insecticides and ovicides, as well as the identification of plastics and resins.
synthesis
A synthesis method of 2,4-dichloro-5-fluorobenzoyl chloride comprises: 2,4-dichlorofluorobenzene, carbon dioxide and carbon tetrachloride are prepared under the action of cationic resin catalyst. The dosage of the cationic resin catalyst is 1%~10% of the mass of 2,4-dichlorofluorobenzene, and the preparation method of the cationic resin catalyst comprises: the cationic resin is first treated with 1mol/L of sodium hydroxide, then washed with hydrochloric acid, washed with water to neutral and then immersed in 0.5mol/LFeCl3 solution and stirred for 5~10 hours, and then HF is added to pH of 2~3; After the reaction system is aged at -3~-6 °C for 20~30h, it is filtered and washed, and then the filter cake is dried at 70~90 °C to obtain the cationic resin catalyst.
Related News
Submitted successfully
We will contact you as soon as possible