Trelagliptin Succinate
Grade: Pharmaceutical Grade Molecular Formula: C22H26FN5O6 Main Use: Pharmaceutical Raw Materials English Name: Trelagliptin succinateAppearance traits: White powder Purity: 99% Shelf life: 24 months CAS Number: 1029877-94-8EINECS Number: / alias: Tropagliptin succinateProduct specifications: 99%
Chinese Name: Trogliptin succinate
Chinese aliases: trogliptin 2
CAS No:1029877-94-8
Molecular Formula: C22H26FN5O6
Appearance white to beige solid
Uses: Using DPP-4 taken from Caco-2 cells as a material, the IC50 of trogliptin was measured to be 5.4nmol/L; Using the plasma DPP-4 of humans, dogs and rats as materials, the IC50s of tradagliptin were measured to be 4.2 nmol/L, 6.2 nmol/L and 9.7 nmol/L, respectively. The inhibitory ability of trogliptin on human DPP-4 recombinant protein was better than that of alogliptin and sitagliptin, with IC50 values of 1.3 nmol/L, 5.3 nmol/L and 16.0 nmol/L, respectively. In enzyme-specific experiments, trogliptin had an effect on DPP-2, DP..
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