Reactive oxygen species (ROS) is O2, with electron products, including oxygen one electron product oxygen anion O2-, two electron product hydrogen peroxide (H2O2), three electron product hydroxyl radical (OH-), nitric oxide, etc., short half-life, fat soluble. Reactive oxygen species in vivo are mainly produced in the transition of mitochondrial electron transport chain from state III to state IV, and the environment of mitochondrial high O2 makes the respiratory chain with high reduction state have electrons leaking out from the substrate end and oxygen end of the respiratory chain, and handed over to O2, and O2- is generated.
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