CAS 7379-35-3

Appearance: White crystalline.

Melting Point: 210 °C (subl.) (lit.)

Flash point 198 °C

Storage conditionsKeep in dark place,Inert atmosphere,Room temperature

Morphological crystalline powder

Color: off-white to yellowish-beige

PH 2.0 (100g/l, H2O, 20°C)

Water solubility is easily soluble in water.

Detection Method: HPLC

BRN3684904

InChIKeyXGAFCCUNHIMIRV-UHFFFAOYSA-N

CAS DataBase Reference7379-35-3

EPA Chemical Substance Information 4-Chloropyridine hydrochloride (7379-35-3)

apply

4-chloropyridine hydrochloride is an important intermediate in organic synthesis, which is widely used in the preparation of new medicines, pesticides, dyes, etc.

use

4-Chloropyridine hydrochloride can be used as a pharmaceutical intermediate in the process of laboratory organic synthesis and chemical and pharmaceutical research and development, and pyridine base can be used to synthesize more than 50 drugs, including antitumor drugs, penicillin, vasodilators, nicotinate, inositol nicotinate, etc.

preparation

Pyridine is used as the starting material, and 4-chloropyridine hydrochloride is synthesized by nitrogen oxidation, nitrification, reduction, and chlorination by four-step organic reaction. The total synthetic yield was 74.3% for the separation and analysis of the organic reactions and related intermediate compounds in each step. The process is as follows:

Preparation of 4-chloropyridine hydrochloride