CAS 503615-07-4

CAS No. 503615-07-4
Molecular components C22H22N4O4 molecular weight 406.43

EINECS No. 948-272

Chemicalbook-8 associated class standards;

Reference substance - impurity reference substance;

Impurity references; Other;

Series 1Mol file 503615-07-4.mol

apixaban (apixaban, 1), chemical identify 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide, is an anticoagulant together developed by way of Bristol-Myers Squibb and Pfizer, which immediately acts on coagulation component Xa, and used to be permitted by using the European Union and FDA in May 2011 and December 2012, respectively. It used to be launched in April 2013 in China Chemicalbook below the alternate identify Alto, which is used to deal with venous thrombotic illnesses such as deep vein thrombosis and pulmonary embolism. Apixaban is the solely more moderen oral anticoagulant authorised for secondary prevention at doses decrease than the preliminary therapeutic dose for VTE. Clinical professionals observe that when thinking about the dangers and advantages of ongoing therapy, sufferers and docs may also welcome anticoagulant regimens for secondary prophylaxis at decrease doses, and sufferers are greater in all likelihood to acquire long-term cure with apixaban. Studies have proven that apixaban is fantastic in treating VTE with fewer bleeding occasions than warfarin.