CAS 50-23-7
11-B,17-A,21-TRIHYDROXY-4-PREGNEN-3,20-DIONE
11BETA,17ALPHA,21-TRIHYDROXYPREGN-4-ENE-3,20-DIONE
17ALPHA-HYDROXYCORTICOSTERONE
17-HYDROXYCORTICOSTERONE
4-PREGNEN-11BETA,11A,21-TRIOL-3,20-DIONE
4-PREGNEN-11-BETA, 17,21-TRIOL-3,20-DIONE
4-PREGNEN-11BETA,17ALPHA,21-TRIOL-3,20-DIONE
4-PREGNEN-3,20-DIONE-11BETA,17ALPHA,21-TRIONE
4-PREGNENE-11B,17A,21-TRIOL-3,20-DIONE
4-PREGNENE-11BETA,17ALPHA,21-TRIOL-3,20-DIONE
(8S,9S,10R,11S,13S,14S,17R)-11,17-DIHYDROXY-17-(2-HYDROXY-ACETYL)-10,13-DIMETHYL-1,2,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE
Appearance: white or off-white crystalline powder, odorless, bitter taste. Deterioration in contact with light. Mp214-220°C (decomposition); Specific rotation [α] 25D+157.5° (dioxane), +176° (chloroform), +162°-+169° (ethanol); The ethanol solution has a maximum absorption at a wavelength of 242 nm. This product is insoluble in water, insoluble in ether, slightly soluble in chloroform, soluble in acetone, ethanol. Soluble in concentrated sulfuric acid solution and green fluorescence. LD50 (rat, intraperitoneal) 150mg/kg.
Melting Point: 211-214 °C(lit.)
Melting Point: 211-214 °C(lit.)
Specific rotation 166 º (c=1, C2H5OH 25 ºC)
Boiling Point: 414.06°C (rough estimate)
Density1.0812 (rough estimate)
refractive index1.6120 (estimate)
Flash point 220 °c
Storage conditions: −20°C
Storage conditions: -20 °C
Solubility H2O: 100 mg/mL
Solubility H2O: 100 mg/mL
Form powder
Color: White
Water solubility: 319.7 mg/L (25 ºC)
Decomposition220 ºC
Merck14,4787
BRN1354819
Stable but may be sensitive to light. Incompatible with strong oxidizing agents.
LogP1.610
CAS DataBase Reference 50-23-7
NIST Chemical Substance Information Hydrocortisone(50-23-7)
EPA Chemical Information Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11.beta.) -(50-23-7)
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