CAS 23964-58-1

Basic information
Chinese name: Atecaine
Chinese aliases: aceclofenac impurity H; Methyl 4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylate; [1]
English name: Articaine;
Methyl (4-methyl-3-(2-(propylamino)propionamido)-2-thiophencarboxylat); 3-(N-propyl-2-amino-propionylamino)-2-carbomethoxy-4-methylthiophene； 4-Methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylic acid,methyl ester； Articaina [INN-Spanish]； Carticaine;
Aticaine compound is a white crystalline powder with the components 4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylate. Clinically, it is an anesthetic drug and is used for anesthesia.
Aticaine compound is a white crystalline powder with the system 4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylate. Clinically, it is an anesthetic drug and is used for anesthesia.

1. The use of this product should first inject a dose of 5%~10% to test whether there is an allergic reaction. [2]

2. Patients receiving anticoagulant therapy must be closely monitored (monitoring the international normalized ratio). [2]

3. High blood pressure, diabetes, pregnant women should use this product with caution. [2]

4. Avoid injecting infected and inflammatory sites. This product may cause local tissue necrosis, and attention should be paid to the risk of anesthesia bite. [2]

5. Because amide local anesthetics are mainly metabolized by the liver, patients with severe liver dysfunction need to reduce the dose. Patients with hypoxia, hyperkalemia, and metabolic acidosis also require dose reduction. [2]

6. This product contains 1/100000 of epinephrine, so the following conditions need to be paid close attention: various types of arrhythmias in addition to bradycardia, coronary insufficiency, severe arterial hypertension.