Sulfadiazine

Sulfadiazine is an natural compound with a molecular formulation of C10H10N4O2S, white or off-white crystals or powders, odorless, tasteless, and step by step darkened when uncovered to light. Almost insoluble in water, soluble in boiling water (1:60), barely soluble in ethanol and acetone, insoluble in chloroform and ether, soluble in dilute hydrochloric acid, sodium hydroxide answer or ammonia solution. Melting factor 252~256 °C (simultaneous decomposition). Its sodium salt is white crystalline powder, odorless, barely bitter taste. Gradient brownish upon light. Left in humid air for a lengthy time, carbon dioxide is slowly absorbed and sulfadiazine is precipitated.
1. Sulfadiazine is the favored drug for the prevention and remedy of meningococcal meningococcal meningitis (meningococcal meningitis).
2. Sulfadiazine is additionally appropriate for the cure of respiratory infections, intestinal infections and nearby smooth tissue infections brought about via touchy bacteria.
3. Sulfadiazine can additionally be used for the remedy of nocardiosis, or in aggregate with pyrimethamine for the therapy of toxoplasmosis.