methyl ester-manufacture,factory,supplier from China

(Total 24 Products for methyl ester)
Basic informationChinese name: AtecaineChinese aliases: aceclofenac impurity H; Methyl 4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylate; [1]English name: Articaine;Methyl (4-methyl-3-(2-(propylamino)propionamido)-2-thiophencarboxylat); 3-(N-propyl-2-amino-propionylamino)-2-carbomethoxy-4-methylthiophene; 4-Methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylic acid,methyl ester; Articaina [INN-Spanish]; Carticaine;Aticaine compound is a white crystalline powder with the formula 4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylate.
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Chinese Name: 2-[(6-chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidine]methyl]butyronitrileEnglish title 2-((6-Chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrileChinese alias alogliptin-B | 2-[(6-Chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]benzonitrile | Alogliptin intermediate | Alogliptin benzoate intermediate 1English aliases morePhysicochemical propertiesDensity 1.4±0.1 g/cm3boiling factor 418.0±55.0 °C at 760 mmHgMolecular formulation C13H10ClN3O2Molecular Weight: 275.690flash factor 206.6±31.5 °CExact
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Appearance: Light yellow crystalline powderMelting Point: 128-130 °C(lit.)Boiling Point:563.2±42.0 °C(Predicted)Density 1.63refractive index1.6200 (estimate)Storage conditions: Refrigerator, Under Inert AtmosphereSolubility soluble in chloroform (a little), methanol (a little)pKa1.22±0.10(Predicted)Morphological solidsThe color is pale yellowStability: Moisture sensitiveInChIKeyCOFDRZLHVALCDU-YVLHZVERSA-NCAS DataBase Reference80756-85-0Brief introductionAE-active ester, chemical name 2-methoxyimino-2-(2-amino-4-thiazolyl)-(z)-thioacetic acid benzothiazole ester.
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Basic informationChinese name: AtecaineChinese aliases: aceclofenac impurity H; Methyl 4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylate; [1]English name: Articaine;Methyl (4-methyl-3-(2-(propylamino)propionamido)-2-thiophencarboxylat); 3-(N-propyl-2-amino-propionylamino)-2-carbomethoxy-4-methylthiophene; 4-Methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylic acid,methyl ester; Articaina [INN-Spanish]; Carticaine;Aticaine compound is a white crystalline powder with the components 4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylate.
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Materialized propertiesDensity:1.52±0.1 g/cm3(Predicted)Boiling point:545.3±50.0 °C(Predicted)PSA:80.65000logP:2.52900Acidity coefficient (PKA):11.15±0.70(Predicted)English alias(S)-Methyl 3-(7-bromo-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanoate1H-1,4-Benzodiazepine-3-propanoic acid, 7-bromo-2,3-dihydro-2-oxo-5-(2- pyridinyl)-, methyl ester, (3S)-(3S)-(7-BroMo-2-oxo-5-pyridin-2-yl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-propionic acid Methyl esterMethyl 3-[(3S)-7-bromo-2-oxo-5-(2- pyridinyl)-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateCAS308242-23-1InchiInC
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Brief introductionAE-active ester, chemical title 2-methoxyimino-2-(2-amino-4-thiazolyl)-(z)-thioacetic acid benzothiazole ester. Appearance: white or mild yellow crystalline powder, melting factor 128130 °C.
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Chinese Name: 2-[(6-chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidine]methyl]butyronitrileEnglish name 2-((6-Chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrileChinese alias alogliptin-B | 2-[(6-Chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]benzonitrile | Alogliptin intermediate | Alogliptin benzoate intermediate 1English aliases more Physicochemical propertiesDensity 1.4±0.1 g/cm3boiling point 418.0±55.0 °C at 760 mmHgMolecular formula C13H10ClN3O2Molecular Weight: 275.690flash point 206.6±31.5 °CExact Mass 275.046143PSA67.79000LogP1.95Vapour
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English alias(S)-Methyl 3-(7-bromo-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanoate1H-1,4-Benzodiazepine-3-propanoic acid, 7-bromo-2,3-dihydro-2-oxo-5-(2- pyridinyl)-, methyl ester, (3S)-(3S)-(7-BroMo-2-oxo-5-pyridin-2-yl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-propionic acid Methyl esterMethyl 3-[(3S)-7-bromo-2-oxo-5-(2- pyridinyl)-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateCAS308242-23-1InchiInChI=1S/C18H16BrN3O3/c1-25-16(23)8-7-15-18(24)22-13-6-5-11(19)10-12(13)17(21-15)14-4-2-3-9-20-14/h2-6,9-10,15H,7-8H2,1H3,(H,22,24)/t15-/m0/s1InChIkeyPITXBYGUVDYTBQ-HNN
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Chinese alias-[[2'-(2,5-Dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylic acid (5-Methyl(R)-2-[[2,4-Dioxo-3-methyl-6-(3-amino-1-piperidinyl)-1,2,3,4-tetrahydro-1-pyrimidinyl]methyl]-4- Flubenzonitrile succinate succinate tragliptin 2 tropagliptin succinate succinate tradagliptin succinate 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-4-fluorobenzonitrile succinateEnglish aliasSYR111472 SuccinateSuccinic acid - 2-({6-[(3R)-3-amino-1-piperidinyl]-3-methyl-2,4-dioxo-3,4-dihydro-1(2H)-pyrimid
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Chinese Name: Trogliptin succinateChinese aliases: trogliptin 2CAS No:1029877-94-8Molecular Formula: C22H26FN5O6Appearance white to beige solidUses: Using DPP-4 taken from Caco-2 cells as a material, the IC50 of trogliptin was measured to be 5.4nmol/L; Using the plasma DPP-4 of humans, dogs and rats as materials, the IC50s of tradagliptin were measured to be 4.2 nmol/L, 6.2 nmol/L and 9.7 nmol/L, respectively.
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Formic acid is an organic substance with the chemical formula HCOOH and a molecular weight of 46.03 , commonly known as formic acid, which is the simplest carboxylic acid. A colorless liquid with a pungent odor. Formic acid is a weak electrolyte, but its aqueous solution is weakly acidic and corrosive, which can stimulate skin blistering. It is usually found in the secretions of bees, certain ants, and caterpillars. It is an organic chemical raw material, also used as a disinfectant and preservative.Formic acid was first developed by J. J. -L.
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N,N-dimethylformamide is an natural compound with the components C3H7NO and is a colorless obvious liquid. It is no longer solely a chemical uncooked fabric with a large vary of uses, however additionally an tremendous solvent with a broad vary of uses.
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Sulfadiazine is an natural compound with a molecular formulation of C10H10N4O2S, white or off-white crystals or powders, odorless, tasteless, and step by step darkened when uncovered to light. Almost insoluble in water, soluble in boiling water (1:60), barely soluble in ethanol and acetone, insoluble in chloroform and ether, soluble in dilute hydrochloric acid, sodium hydroxide answer or ammonia solution. Melting factor 252~256 °C (simultaneous decomposition).
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Guanidine acetate glycine and its derivatives, functional accelerator, does not contain any illegal drugs, no toxic substances, safe to use without discontinuation period.Appearance shape: white or yellowish powder, the carrier will cause the appearance color to change, but does not affect the effect of the product.Mechanism of action Guanidinoacetic acid is a precursor to creatine. Phosphocreatine containing high phosphate group transfer potential energy is widely present in muscle and nerve tissues, and is the main energy supply substance in animal muscle tissues.
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Pharmacology and toxicologyWhen the plasma awareness exceeds 5 μg·mL-1, convulsions can occur, and at low doses, it can promote the outflow of K+ in myocardial cells, minimize the auto-discipline of the myocardium, and have anti-ventricular arrhythmic effect; At therapeutic doses, there is no full-size impact on the electrical endeavor of cardiomyocytes, atrioventricular conduction and contraction of myocardium; Further enlarge in blood awareness can reason slowing of cardiac conduction velocity, atrioventricular block,
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Chinese name: citric acidChinese synonyms citric acid / citric acid; Citric anhydride; Citrate, anhydrous; Citric acid standards; Citric acid, ACS grade; Citric acid anhydrous, water-contained; Citric acid, anhydrous, ACS grade; Anhydrous citric acid standardEnglish identify CitricacidEnglish synonyms BETZ6251; BETZ0623; BORICACID-POTASSIUMCHLORIDE-SODIUMHYDROXIDEBUFFER; BUFFERCONCENTRATE,PH7.00; BUFFERCONCENTRATE,PH8.00; BUFFERCONCENTRATE,PH9.00; BUFFERCONCENTRATE,PHOSPHATE/SODIUMHYDROXIDE; BUFFERCONCENTRATE,POTASSIUMCHLORIDE/SODIUMHYDROXIDECAS wide variety 77-92-9The mole
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Hydrazine hydrate, additionally recognised as hydrazine hydrate, is a colorless and obvious oily liquid with a mild ammonia smell, smoke in humid air, and is exceedingly alkaline and hygroscopic.
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In 1929, Daim located that there are two types of diet K in nature, K1 and K2, each of which are naphthoquinone compounds. Vitamin K2 is a naturally going on nutrition containing the simple shape of menaquinone and has anti-bleeding effects, yellow crystal or oily liquid at room temperature, insoluble in water, soluble in natural solvents and vegetable oils, heat-resistant, however effortless to be damaged via light.
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In 1929, Daim discovered that there are two kinds of vitamin K in nature, K1 and K2, both of which are naphthoquinone compounds. Vitamin K2 is a naturally occurring vitamin containing the basic structure of menaquinone and has anti-bleeding effects, yellow crystal or oily liquid at room temperature, insoluble in water, soluble in organic solvents and vegetable oils, heat-resistant, but easy to be damaged by light. It can promote the synthesis of prothrombin in the liver and regulate the synthesis of coagulation factors VII., IX., and X., thereby accelerating blood clotting.
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Salicylic acid, a sort of natural acid, chemical method C7H6O3, is a white crystalline powder, barely soluble in bloodless water, effortlessly soluble in warm water, ethanol, ether and acetone, soluble in warm benzene, commonly used as medicine, spices, dyes, pesticides, rubber components and different essential uncooked substances of great chemicals.1.
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Hydrazine hydrate, also known as hydrazine hydrate, is a colorless and transparent oily liquid with a light ammonia smell, smoke in humid air, and is highly alkaline and hygroscopic.
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Basic informationChemical formula: C4H4O4Molecular Weight: 116.072CAS number: 110-17-8EINECS number: 203-743-0Physical and chemical propertiesPhysicalDensity: 1.63g/cm3Melting point: 298-300°CBoiling point: 355.5 °cFlash point: 183 °cRefractive index: 1.526(20°C)Appearance: white powder or colorless crystalsSolubility: soluble in ethanol, barely soluble in water and ether, insoluble in chloroform, carbon tetrachloride, benzeneChemical propertiesThe easiest unsaturated dicarboxylic acid.
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Product Category: Chemical Intermediates - Other Intermediates Cas Number: 21739-92-4Product Specifications: 99% Packing: 25 kg Brand: Runde Detailed Description:5-Bromo-2-chlorobenzoic acidChinese synonyms: 2-Chloro-5-bromobenzoic acid; 5-Bromo-2-chlorobenzoic acid; 5-Bromo-2-chlorobenzoic acid; 5-BroMo-2-chlorobenzoic acid, 98+%; 5-Bromo-2-chlorobenzoic acid; 2-Chloro-5-bromobenzoic acid, 99.86%; 5-Bromo-2-chlorobenzoic acid/2-chloro-5-bromobenzoic acid; 5-BroMo-2-chlorobenzoic acid, 98+%Name: 5-Bromo-2-chlorobenzoic acidEnglish synonyms:Benzoic acid, 5-bromo-2-chloro-; 2-CHLORO-5-BROMOBENZO
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S-3-Hydroxytetrahydrofuran [1]English name: S-3-hydroxytetrahydrofuranChinese aliases: (S)-(+)3-hydroxy-tetrahydrofuran; (S)-(+)-3-Hydroxytetrahydrofuran; (S)-3-Hydroxytetrahydrofuran;S-3-Hydroxytetrahydrofuran; Afatinib intermediatesSYNONYMS: (S)-(+)-3-HYDROXY TETAHYDRO FURAN; (S)-(-)-3-HYDROXY TETRAHYDRO FURAN; S-(+)-3-HYDROXYTETRAHYDROFURAN; (S)-3-Hydroxyterthydrofurane; S-(+)-3-Hydroxytetrahydofuran; (2S)-2-Hydroxy-1,4-epoxybutane; (3S)-3-Hydroxytetrahydrofuran; (2S)-1,4-Epoxy-2-hydroxybutane; Afatinib intermediatesCAS:86087-23-2Molecular formula: C4H8O2Molecular weight: 88.11Assay: 98%Pro
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I. Overview of chemical and pharmaceutical intermediatesChemical pharmaceutical intermediates are a very important part of the pharmaceutical industry, referring to raw materials or semi-finished products in the pharmaceutical industry. These substances undergo a series of chemical reactions to eventually form pharmaceutical products. These chemicals usually exist in liquid or solid form and belong to various types of organic compounds such as acids, alcohols, carboxylic acids, phenols, cork and so on.
Shandong is one of the important pharmaceutical production bases in the country, and the production production is relatively concentrated. The treatment of Shandong Pharmaceutical Intermediate waste is essential for protecting the environment, human health, and sustainable enterprise. This article will discuss how to properly handle waste in the production of Shandong pharmaceutical intermediates.First, reasonable classification and storage wasteReasonable classification and storage waste are the first step in waste treatment.
April 23, 2020. Customized in the middle of Shandong Pharmaceutical. The so -called Shandong pharmaceutical intermediate is actually some chemical raw materials or chemical products for drug synthesis process. This kind of chemical product does not require the production license of drugs. It can be produced in ordinary chemical plants. As long as it reaches some levels, it can be used for the synthesis of drugs.There are more than 2,000 raw materials and intermediates that need to be matched with chemicals each year, with more than 2.5 million tons.
May 13, 2020. Pharmaceutical intermediate body fluorine customized. Pharmaceutical fluorine: colorless liquid. The melting point -42 ℃. Boiling point 85 ° C. Refractive index (ND20) 1.4650. Relators (D420) 1.024. Insuvenate in water and mixes with ethanol, ether, acetone, and benzene. Apineine reacts through Schiemann (G. Schiemann).Ah. After the aniline was descended to -8 ° C after 31%hydrochloride, and the sodium nitrite solution was nitroded.
Medicine intermediate refers to a compound generated as an intermediate step in the process of synthetic drugs. It has high purity and activity, which can synthesize target drugs through further chemical reactions. Medicine intermediates are widely used in the pharmaceutical industry, covering multiple fields. The classification of pharmaceutical intermediates and its application areas will be introduced below.1. Carboxylic acid intermediate:The intermediate of the carboxylic acid refers to the compound of the carboxylic acid group, and the common ones are benzoic acid and propylic acid.
Intermediate production of chemical medicine is a work involving a large number of chemicals. If it is not managed and controlled correctly, it may bring serious risks and pollution to the environment. In order to reduce environmental risks in the production of chemical medicine, we need to improve and control from the following aspects.First, establish a scientific and standardized production process. The production of chemical medicine needs to go through multiple steps and reactions. Each step needs to carefully evaluate and formulate corresponding operating procedures.