Pharmacology and toxicologyWhen the plasma concentration exceeds 5 μg·mL-1, convulsions can occur, and at low doses, it can promote the outflow of K+ in myocardial cells, reduce the auto-discipline of the myocardium, and have anti-ventricular arrhythmic effect; At therapeutic doses, there is no significant effect on the electrical activity of cardiomyocytes, atrioventricular conduction and contraction of myocardium; Further increase in blood concentration can cause slowing of cardiac conduction velocity, atrioventricular block, inhibition of myocardial contractility and decrease of cardiac out
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Pharmacology and toxicologyThis product is an amide local anesthetic. After blood absorption or intravenous administration, it has obvious excitation and inhibition biphasic effect on the central nervous system, and there can be no precursor excitement, when the blood concentration is low, analgesia and drowsiness, and the pain threshold is increased; With the increase of dose, the effect or toxicity increases, and there is an anticonvulsant effect at the concentration of subtoxic blood drugs; When the blood concentration exceeds 5 mg·mL-1, convulsions can occur.
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Fields of applicationPurpose 1It is suitable for vitamin B1 deficiency, has the function of maintaining normal glucose metabolism and nerve conduction, and is also used for the adjuvant treatment of dyspepsia and neuritisPreparation method:Method 1Thiamine hydrochloride is usually obtained by condensation, hydrolysis, neutralization, oxidation, and acidification of excess acetamidine hydrochloride with α-dimethoxy β-methoxypropionitrile.Upstream and downstream product informationUpstream raw materialsEthanol, hydrogen peroxide, dimethyl sulfate, ethyl chlorosulfonate, acrylonitrile, carboxylat
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Pharmacological actionSince the discovery that long-acting local anesthetics can induce cardiac arrest, people have been looking for safer alternatives with less fat solubility. Ropivacaine is such a new long-acting amide local anesthetic, which has a long duration of action and has anesthetic and analgesic effects. Its pharmacological characteristics are low cardiotoxicity, sensory block and motor block are clearly separated, and it has peripheral vasoconstriction effect.
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apply4-chloropyridine hydrochloride is an important intermediate in organic synthesis, which is widely used in the preparation of new medicines, pesticides, dyes, etc.use4-Chloropyridine hydrochloride can be used as a pharmaceutical intermediate in the process of laboratory organic synthesis and chemical and pharmaceutical research and development, and pyridine base can be used to synthesize more than 50 drugs, including antitumor drugs, penicillin, vasodilators, nicotinate, inositol nicotinate, etc.preparationPyridine is used as the starting material, and 4-chloropyridine hydrochloride is syn
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Appearance: White crystalline.Melting Point: 210 °C (subl.) (lit.)Flash point 198 °CStorage conditionsKeep in dark place,Inert atmosphere,Room temperatureMorphological crystalline powderColor: off-white to yellowish-beigePH 2.0 (100g/l, H2O, 20°C)Water solubility is easily soluble in water.Detection Method: HPLCBRN3684904InChIKeyXGAFCCUNHIMIRV-UHFFFAOYSA-NCAS DataBase Reference7379-35-3EPA Chemical Substance Information 4-Chloropyridine hydrochloride (7379-35-3)apply4-chloropyridine hydrochloride is an important intermediate in organic synthesis, which is widely used in the preparation of new
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Chinese name: 1-[[2-(4-chlorophenyl)ethyl]amino]-2-chloropropane hydrochloride Chinese synonymous with green casserin intermediate; Lorcaserin intermediate 2; Lorcaserin Impurity B; 1-[[2-(4-chlorophenyl)ethyl]amino]-2-chloropropane hydrochloride; Lorcaserin hydrochloride intermediate 2; 2-Chloro-N-(4-chlorophenethyl)propan-1-amine chloride; Lorcaserin impurity B (EP); Chlorocasein Impurity B English name 1-[[2-(4-Chlorophenyl)ethyl]amino]-2-chloropropane English synonym 1-[[2-(4-Chlorophenyl)ethyl]amino]-2-chloropropane; 1-[[2-(4-Chlorophenyl)ethyl]amino]-2-chloropropaneHydrochloride; Benzene
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Chinese name: 1-[[2-(4-chlorophenyl)ethyl]amino]-2-chloropropane hydrochloride Chinese synonymous with inexperienced casserin intermediate; Lorcaserin intermediate 2; Lorcaserin Impurity B; 1-[[2-(4-chlorophenyl)ethyl]amino]-2-chloropropane hydrochloride; Lorcaserin hydrochloride intermediate 2; 2-Chloro-N-(4-chlorophenethyl)propan-1-amine chloride; Lorcaserin impurity B (EP); Chlorocasein Impurity B English title 1-[[2-(4-Chlorophenyl)ethyl]amino]-2-chloropropane English synonym 1-[[2-(4-Chlorophenyl)ethyl]amino]-2-chloropropane; 1-[[2-(4-Chlorophenyl)ethyl]amino]-2-chloro
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CAS 39263-32-6 Purity 98%Molecular weight 197.04 Molecular formula C7H5BrN2Leadtime In stock Size gItem No. 1031675 Application Chemical, bioindustry, pharmaceuticalFor more product specifications, please consult customer service; Product Name: 2-Amino-5-bromobenzonitrile_Leyan reagent; CAS:39263-32-6; Molecular Formula: C7H5BrN2; Molecular weight: 197.04; storage conditions: 2-8 °C, protect from light2-Amino-5-bromobenzonitrileCAS No.
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Sodium gluconate is a type of natural matter, chemical components C6H11NaO7, in the enterprise is very extensively used, sodium gluconate can be used in construction, fabric printing and dyeing and metallic floor cure and water remedy industries as environment friendly chelating agent, metal floor cleansing agent, glass bottle cleansing agent, electroplating industrial aluminum oxide coloring, in the concrete enterprise as a excessive effectivity
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Sodium hyaluronate, chemical system (C14H20NO11Na)n, is an inherent thing of the human body, is a glucuronic acid, no particular species, it is extensively current in placenta, amniotic fluid, lens, articular cartilage, pores and skin dermis and different tissues and organs. It is disbursed in the cytoplasm and interstitium, which lubricates and nourishes the cells contained in it and the cell organs themselves.It additionally presents a microenvironment for cellphone metabolism.
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Sulfadiazine is an organic compound with a molecular formula of C10H10N4O2S, white or off-white crystals or powders, odorless, tasteless, and gradually darkened when exposed to light. Almost insoluble in water, soluble in boiling water (1:60), slightly soluble in ethanol and acetone, insoluble in chloroform and ether, soluble in dilute hydrochloric acid, sodium hydroxide solution or ammonia solution. Melting point 252~256 °C (simultaneous decomposition). Its sodium salt is white crystalline powder, odorless, slightly bitter taste. Gradient brownish upon light.
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2,3,4,5-TETRAFLUORBENZOYLCHLORID2,3,4,5-TETRAFLUOROBENZOYL CHLORIDEBenzoyl chloride, 2,3,4,5-tetrafluoro- (9CI)2,3,4,5-Tetrafluorobenzoyl2,3,4,5-Tetrafluorobenzoyl chloride 98%2,3,4,5-TETRAFLUOROBEZOYL CHLORIDE2,3,4,5-Tetrafluorobenzoylchloride98%94-24-62,3,4,5-Tetrafluorobenzoic acid chlorideBoiling point 65-66 °C 10mmDensity: 1.58 g/mL at 25 °C(lit.)Refractive index n20/D 1.4787(lit.)Flash point 194 °FSpecific gravity 1.580Sensitivity: Moisture sensitivityBRN5266860InChIKeyXWCKIXLTBNGIHV-UHFFFAOYSA-NCAS DataBase Reference94695-48-4
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2,3,4,5-TETRAFLUORBENZOYLCHLORID2,3,4,5-TETRAFLUOROBENZOYL CHLORIDEBenzoyl chloride, 2,3,4,5-tetrafluoro- (9CI)2,3,4,5-Tetrafluorobenzoyl2,3,4,5-Tetrafluorobenzoyl chloride 98%2,3,4,5-TETRAFLUOROBEZOYL CHLORIDE2,3,4,5-Tetrafluorobenzoylchloride98%94-24-62,3,4,5-Tetrafluorobenzoic acid chlorideBoiling point 65-66 °C 10mmDensity: 1.58 g/mL at 25 °C(lit.)Refractive index n20/D 1.4787(lit.)Flash point 194 °FSpecific gravity 1.580Sensitivity: Moisture sensitivityBRN5266860InChIKeyXWCKIXLTBNGIHV-UHFFFAOYSA-NCAS DataBase Reference94695-48-4
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Boiling Point: 143-144 °C35 mm Hg(lit.)Density: 1.568 g/mL at 25 °C(lit.)Refractive index n20/D 1.572(lit.)Flash point > 230 °FSpecific gravity 1.568Sensitivity: Moisture sensitivityBRN4989077CAS DataBase Reference: 86393-34-2use2,4-Dichloro-5-fluorobenzoyl chloride is the main raw material for the preparation of third-generation quinolones such as trifluoroperidinol, trifluoroguabutenyl, pentafluridol and synthetic broad-spectrum antibiotics such as ciprofloxacin, and can also be used for pesticides, insecticides and ovicides, as well as the identification of plastics and resins.synthesisA
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Chinese title nitrobenzeneEnglish title nitrobenzeneEnglish aliases moreNitrobenzene physicochemical propertiesDensity 1.205boiling factor 210-211 °C(lit.)melting factor 5-6 °C(lit.)Molecular Formula C6H5NO2Molecular Weight: 123.10900Flash factor one hundred ninety °FExact mass 123.03200PSA 45.82000LogP 2.11800Appearance qualities yellow liquidVapor density 4.2 (vs air)Vapour stress 0.15 mm Hg ( 20 °C)refractive index n20/D 1.551(lit.)Storage conditionsStorage precautions Store in a cool, ventilated warehouse.
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CAS 39263-32-6 Purity 98%Molecular weight 197.04 Molecular components C7H5BrN2Leadtime In inventory Size gItem No. 1031675 Application Chemical, bioindustry, pharmaceuticalFor greater product specifications, please seek advice from consumer service; Product Name: 2-Amino-5-bromobenzonitrile_Leyan reagent; CAS:39263-32-6; Molecular Formula: C7H5BrN2; Molecular weight: 197.04; storage conditions: 2-8 °C, guard from light2-Amino-5-bromobenzonitrileCAS No.
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Purpose 1used as pharmaceutical raw materials, health care products, intermediates, food additives, etcPurpose 2D-ribose is an important component of nucleic acid, the genetic material in living organisms, which occupies a pivotal position in the metabolism of nucleosides, proteins and fats, and has important physiological functions and broad application prospects. As a natural component of all cells in living organisms, D-ribose is closely related to the formation of adenylate and the regeneration of ATP, and is one of the most basic sources of energy for life metabolism.
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Chinese Name: Trogliptin succinateChinese aliases: trogliptin 2CAS No:1029877-94-8Molecular Formula: C22H26FN5O6Appearance white to beige solidUses: Using DPP-4 taken from Caco-2 cells as a material, the IC50 of trogliptin was measured to be 5.4nmol/L; Using the plasma DPP-4 of humans, dogs and rats as materials, the IC50s of tradagliptin were measured to be 4.2 nmol/L, 6.2 nmol/L and 9.7 nmol/L, respectively.
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N,N-dimethylformamide is an organic compound with the formula C3H7NO and is a colorless transparent liquid. It is not only a chemical raw material with a wide range of uses, but also an excellent solvent with a wide range of uses.
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Anilidine, also known as aminobenzene, is an organic compound, chemical formula C6H7N, is a colorless oily liquid, heated to 370 °C decomposition, slightly soluble in water, soluble in ethanol, ether and other organic solvents.Aniline is one of the most important amines. It is mainly used in the manufacture of dyes, drugs, resins, and can also be used as rubber vulcanization accelerators. It itself can also be used as a black dye.
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Chinese name thiopronin Chinese synonymous N-(2-mercaptopropionyl)-glycine; Thiopron; Tiopronin; N-(2-Mercaptopropionyl)glycine; mercaptopropionylglycine; Thiopronin impurities; (±)-N-(2-mercapto-1-oxopropyl)glycine; TIOPRONIN English name Tiopronin English synonym A-MERCAPTOPROPIONYL GLYCINE; ALPHA-MERCAPTO PROPIONYL GLYCINE; LABOTEST-BB LT00451995; TIOPRONIN; N-(2-MERCAPTOPROPIONYL)GLYCINE; TOPRONIN; (2-Mercaptopropionamido)acetic acid; (2-Mercaptopropionyl)glycineCAS1953-02-2Molecular formula C5H9NO3S molecular weight 163.19EINECS217-778-4 related categories of medical raw materials; medica
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Cloxazon, chemical name 5-chloro-2-benzoxazolidone, molecular formula C7H4ClNO2, is a muscle relaxant acting on the center, used for various acute and chronic soft tissue (muscle, ligament) sprains, contusions, muscle aches after exercise, muscle spasms caused by central neuropathy and chronic fasciitis.【Chinese alias】Muscle relaxant; Chlordobenazole; 5-Chloro-2-hydroxybenzoxazole; Chloroxazolone; Chlordobenazole; Chlordobenazole; 5-Chloro-2-benzoxazolinone; 5-Chloro-2-benzoxazolone; 6-Chlorobenzoxazolone.【Molecular Formula】C7H4ClNO2 【Molecular Weight】169.57 【CAS】95-25-0【Usage and dosage】Oral:
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TriacetateGlyceryl triacetate is an organic compound with a C9H14O6 molecular formula, colorless and odorless oily liquid, miscible with ethanol, ether, chloroform and benzene, slightly soluble in water and carbon disulfide. Used as cigarette filter binder and fragrance fixative, solvent, toughening agent. And can be used in cosmetics, casting, medicine, dyes and other industries.
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