Duncainehydrochloride-manufacture,factory,supplier from China

(Total 24 Products for Duncainehydrochloride)
Chinese Name: Trogliptin succinateChinese aliases: trogliptin 2CAS No:1029877-94-8Molecular Formula: C22H26FN5O6Appearance white to beige solidUses: Using DPP-4 taken from Caco-2 cells as a material, the IC50 of trogliptin was measured to be 5.4nmol/L; Using the plasma DPP-4 of humans, dogs and rats as materials, the IC50s of tradagliptin were measured to be 4.2 nmol/L, 6.2 nmol/L and 9.7 nmol/L, respectively.
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Clonazepam , with the formula C15H10ClN3O3 , is a benzodiazepine tranquilizer. Clinically, it is mainly used for: (1) treatment of epilepsy and convulsions, which are effective for all types of epilepsy, especially for small seizures and myoclonic seizures. Intravenous treatment of status epilepticus. (2) Treatment of anxiety and insomnia. (3) It is also effective for choreas. It also has a certain effect on drug-induced hyperactivity, chronic multiple convulsions, stiff man syndrome, and various types of neuralgia.The effect is similar to diazepam and nitrazepam.
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Reactive oxygen species (ROS) is O2, with electron products, including oxygen one electron product oxygen anion O2-, two electron product hydrogen peroxide (H2O2), three electron product hydroxyl radical (OH-), nitric oxide, etc., short half-life, fat soluble.
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Appearance: yellow or orange-yellow crystalline powder; Odorless and tasteless; It is easy to decompose when exposed to lightMelting point 49-51 °cBoiling Point: 715.32°C (rough estimate)Density0.9145 (rough estimate)refractive index: 1.4760 (estimate)Storage conditions: −20°CSolubility is easily soluble in chloroform.Morphological neatColor: light orange to dark orangeSensitive to photosMerck9843BRN1900141Stable but may be sensitive to light or heat. Store at -20°C protected from light.
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melting point:248 °C (decomp)Density1.3175 (rough estimate)refractive index1.5630 (estimate)Storage conditionsKeep in dark place,Inert atmosphere,Room temperatureSolubility DMSO : 6 mg/mL (19.95 mM)InChIInChI=1S/C12H17N4OS.
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Phentermine (Phentermine), an organic compound with a molecular formula of C10H15N, is clinically used as an anorexia (diet drug) for the short-term treatment of moderate to severe obesity, and is listed as a Class II psychotropic drug controlBasic informationChinese name: phentermineEnglish name: phentermineMolecular structure dataMolar refractive index: 48.56Molar volume (cm3/mol): 158.9Isotonic specific volume (90.2K): 387.5Surface tension (dyne/cm): 35.3Polarizability (10-24cm3): 19.25 [5]Flash point: 93.1ºCRefractive index: 1.523Vapour pressure: 0.243mmHg at 25°C CAS number: 122-09-8
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CAS:21739-92-4Product Category: Chemical Intermediates - Other Intermediates Cas Number: 21739-92-4Product Specifications: 99% Packing: 25 kg Brand: Runde Detailed Description:5-Bromo-2-chlorobenzoic acidChinese synonyms: 2-Chloro-5-bromobenzoic acid; 5-Bromo-2-chlorobenzoic acid; 5-Bromo-2-chlorobenzoic acid; 5-BroMo-2-chlorobenzoic acid, 98+%; 5-Bromo-2-chlorobenzoic acid; 2-Chloro-5-bromobenzoic acid, 99.86%; 5-Bromo-2-chlorobenzoic acid/2-chloro-5-bromobenzoic acid; 5-BroMo-2-chlorobenzoic acid, 98+%Name: 5-Bromo-2-chlorobenzoic acidEnglish synonyms:Benzoic acid, 5-bromo-2-chloro-; 2-CHLOR
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CAS 39263-32-6 Purity 98%Molecular weight 197.04 Molecular formula C7H5BrN2Leadtime In stock Size gItem No. 1031675 Application Chemical, bioindustry, pharmaceuticalFor more product specifications, please consult customer service; Product Name: 2-Amino-5-bromobenzonitrile_Leyan reagent; CAS:39263-32-6; Molecular Formula: C7H5BrN2; Molecular weight: 197.04; storage conditions: 2-8 °C, protect from light2-Amino-5-bromobenzonitrileCAS No.
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Purpose 1Salicylic acid and acetic acid. Slightly soluble in water, soluble in ethanol, ether, chloroform, also soluble in hydroxide alkali solution or carbonic acid solution, and decompose at the same time. Commonly used antipyretic analgesics.
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Sulfadiazine is an organic compound with a molecular formula of C10H10N4O2S, white or off-white crystals or powders, odorless, tasteless, and gradually darkened when exposed to light. Almost insoluble in water, soluble in boiling water (1:60), slightly soluble in ethanol and acetone, insoluble in chloroform and ether, soluble in dilute hydrochloric acid, sodium hydroxide solution or ammonia solution. Melting point 252~256 °C (simultaneous decomposition). Its sodium salt is white crystalline powder, odorless, slightly bitter taste. Gradient brownish upon light.
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Chemical propertiesFormaldehyde and resorcinol react under alkaline conditions to form orange-red compounds, which are colorimetric at a maximum absorption wavelength of 460nm to detect low traces of formaldehyde in textile and clothing.Since resorcinol can undergo enol and ketone form tautomerism, it can react with ammonia as follows:Ketone reaction of resorcinolUnder the action of ammonia, m-phenyltriamine is obtained by reaction in ketone, and the amine is hydrolyzed in the aqueous solution of acid to obtain resorcinol.
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Trehalose, also known as fenose and fungose, is a non-reducing disaccharide composed of two glucose molecules with the molecular formula C12H22O11 [8].
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CAS:86087-23-2S-3-Hydroxytetrahydrofuran [1]English name: S-3-hydroxytetrahydrofuranChinese aliases: (S)-(+)3-hydroxy-tetrahydrofuran; (S)-(+)-3-Hydroxytetrahydrofuran; (S)-3-Hydroxytetrahydrofuran;S-3-Hydroxytetrahydrofuran; Afatinib intermediatesSYNONYMS: (S)-(+)-3-HYDROXY TETAHYDRO FURAN; (S)-(-)-3-HYDROXY TETRAHYDRO FURAN; S-(+)-3-HYDROXYTETRAHYDROFURAN; (S)-3-Hydroxyterthydrofurane; S-(+)-3-Hydroxytetrahydofuran; (2S)-2-Hydroxy-1,4-epoxybutane; (3S)-3-Hydroxytetrahydrofuran; (2S)-1,4-Epoxy-2-hydroxybutane; Afatinib intermediatesCAS:86087-23-2Molecular formula: C4H8O2Molecular weight: 88.1
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Heptoic,acidhexacidc-7,Hexacid, C-7n-heptanoic,heptoicacid,Hepthlic, acidEnanthic, AcidOenanthic, acidEnanthylic acidHeptylic acid1-Hexanecarboxylic acidn-Heptoic acidOenanthylic acidEnanthoic acidNSC 2192n-Heptanoic acidn-Heptylic acidProduction methods and usesmethod GC,NMRHeptanaldehyde is carbonylated from 1-hexene with syngas (CO+H2), and then oxidized by air.Heptanaldehyde is prepared by carbonylation of heptene-1 and syngas, and then heptanoic acid is obtained by air oxidation.
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Purpose 1Biochemical studies, adrenocorticosteroid drugs.Purpose 2Glucocorticoids have four major effects: anti-inflammatory, anti-allergic, anti-toxin, and anti-shock.Purpose 3The adrenal cortex secretes the main glucocorticoid, which has three times the anti-inflammatory power of corticosterone.Refer to quality standardsThe content is 96%-104%, mp212-220°C, the specific rotation [α] 20D+161°-+169°, the absorbance coefficient (A) is 428-450, and the content of impurities such as loss on drying and burning residue is detected.
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Heptoic,acidhexacidc-7,Hexacid, C-7n-heptanoic,heptoicacid,Hepthlic, acidEnanthic, AcidOenanthic, acidEnanthylic acidHeptylic acid1-Hexanecarboxylic acidn-Heptoic acidOenanthylic acidEnanthoic acidNSC 2192n-Heptanoic acidn-Heptylic acidProduction methods and usesmethodGC,NMRHeptanaldehyde is carbonylated from 1-hexene with syngas (CO+H2), and then oxidized by air.Heptanaldehyde is prepared by carbonylation of heptene-1 and syngas, and then heptanoic acid is obtained by air oxidation.
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Sodium hyaluronate, chemical formula (C14H20NO11Na)n, is an inherent component of the human body, is a glucuronic acid, no specific species, it is widely present in placenta, amniotic fluid, lens, articular cartilage, skin dermis and other tissues and organs. It is distributed in the cytoplasm and interstitium, which lubricates and nourishes the cells contained in it and the cellular organs themselves.It also provides a microenvironment for cell metabolism.
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Method 1Its preparation methods are as follows:2,4-disulfophenol alkali melt hydrolysis method;o-chlorophenol hydrolysis;phenol direct oxidation;phenolic oxidation;O-hydroxycyclohexanone dehydroaromatization.Among them, (1) and (2) the process is complex, the three wastes are polluted, and they are gradually replaced by new processes, while methods (4) and methods (5) are being industrialized abroad.
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Chemical composition informationINCI: 1,2-Hexanediol (1,2-Hexanediol)CAS No.:6920-22-5Molecular formula: C₆ H₁₄ O₂Molecular weight: 118.18g/molSpecific parametersAppearance: colorless obvious liquidOdor: totally odorlessPurity: >99.8%Water content: <0.2%Relative density (20°C): 0.946-0.956 g/cmRefractive index (25°C): 1.437-1.447pH (25°C): 6.5±0.5Boiling point: 223-224°C (at 760.00mm Hg)Air pressure: 9mbar (at 108°C)Flash point: 122°CMelting point: forty five °cStorage: Sealed storage in a cool location away from mild and keep away f
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Basic informationChemical formula: C4H4O4Molecular Weight: 116.072CAS number: 110-17-8EINECS number: 203-743-0Physical and chemical propertiesPhysicalDensity: 1.63g/cm3Melting point: 298-300°CBoiling point: 355.5 °cFlash point: 183 °cRefractive index: 1.526(20°C)Appearance: white powder or colorless crystalsSolubility: soluble in ethanol, slightly soluble in water and ether, insoluble in chloroform, carbon tetrachloride, benzeneChemical propertiesThe simplest unsaturated dicarboxylic acid. First found in fusso, it is also found in many kinds of mushrooms and fresh beef.
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Appearance: white or off-white crystalline powder, odorless, bitter taste. Deterioration in contact with light. Mp214-220°C (decomposition); Specific rotation [α] 25D+157.5° (dioxane), +176° (chloroform), +162°-+169° (ethanol); The ethanol solution has a maximum absorption at a wavelength of 242 nm. This product is insoluble in water, insoluble in ether, slightly soluble in chloroform, soluble in acetone, ethanol. Soluble in concentrated sulfuric acid solution and green fluorescence.
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Sodium hyaluronate, chemical system (C14H20NO11Na)n, is an inherent thing of the human body, is a glucuronic acid, no particular species, it is extensively current in placenta, amniotic fluid, lens, articular cartilage, pores and skin dermis and different tissues and organs. It is disbursed in the cytoplasm and interstitium, which lubricates and nourishes the cells contained in it and the cell organs themselves.It additionally presents a microenvironment for cellphone metabolism.
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Cyclohexanone is an organic compound with the formula C6H10O , a saturated cyclic ketone with carbonyl carbon atoms included in a six-membered ring. Colorless transparent liquid with earthy smell, with mint smell when containing trace amounts of phenol. Impurities are light yellow, which develop color with the formation of impurities during storage time, and are water-white to gray-yellow, with a strong pungent odor. Mixed with air, the explosive pole is the same as open-chain saturated ketone.
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Appearance characteristicsThis product is white crystal, m.p.138~140 °C, insoluble in water, soluble in alcohol, ether, etc.Melting Point: 134-136 °C (lit.)Melting Point: 134-136 °C(lit.)Boiling Point: 272.96°C (rough estimate)Density 1.35Density 1.35refractive index1.4500 (estimate)Flash point 250 °CFlash point 250 °CStorage conditions: 2-8 °CStorage conditionsStore at RT.Solubility H2O: 10 mg/mL at 37 °CSolubility in water Solubility 10 mg/mLat 37 °CMorphological crystallineThe color is whiteAcidity coefficient (pKa): 3.5 (at 25°C)Water solubility: 3.3 g/L (20 ºC)Merck14,851BRN779271Exposure
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I. Overview of chemical and pharmaceutical intermediatesChemical pharmaceutical intermediates are a very important part of the pharmaceutical industry, referring to raw materials or semi-finished products in the pharmaceutical industry. These substances undergo a series of chemical reactions to eventually form pharmaceutical products. These chemicals usually exist in liquid or solid form and belong to various types of organic compounds such as acids, alcohols, carboxylic acids, phenols, cork and so on.
Intermediate production of chemical medicine is a work involving a large number of chemicals. If it is not managed and controlled correctly, it may bring serious risks and pollution to the environment. In order to reduce environmental risks in the production of chemical medicine, we need to improve and control from the following aspects.First, establish a scientific and standardized production process. The production of chemical medicine needs to go through multiple steps and reactions. Each step needs to carefully evaluate and formulate corresponding operating procedures.
April 23, 2020. Customized in the middle of Shandong Pharmaceutical. The so -called Shandong pharmaceutical intermediate is actually some chemical raw materials or chemical products for drug synthesis process. This kind of chemical product does not require the production license of drugs. It can be produced in ordinary chemical plants. As long as it reaches some levels, it can be used for the synthesis of drugs.There are more than 2,000 raw materials and intermediates that need to be matched with chemicals each year, with more than 2.5 million tons.
Medicine intermediate refers to a compound generated as an intermediate step in the process of synthetic drugs. It has high purity and activity, which can synthesize target drugs through further chemical reactions. Medicine intermediates are widely used in the pharmaceutical industry, covering multiple fields. The classification of pharmaceutical intermediates and its application areas will be introduced below.1. Carboxylic acid intermediate:The intermediate of the carboxylic acid refers to the compound of the carboxylic acid group, and the common ones are benzoic acid and propylic acid.
May 13, 2020. Pharmaceutical intermediate body fluorine customized. Pharmaceutical fluorine: colorless liquid. The melting point -42 ℃. Boiling point 85 ° C. Refractive index (ND20) 1.4650. Relators (D420) 1.024. Insuvenate in water and mixes with ethanol, ether, acetone, and benzene. Apineine reacts through Schiemann (G. Schiemann).Ah. After the aniline was descended to -8 ° C after 31%hydrochloride, and the sodium nitrite solution was nitroded.
Shandong is one of the important pharmaceutical production bases in the country, and the production production is relatively concentrated. The treatment of Shandong Pharmaceutical Intermediate waste is essential for protecting the environment, human health, and sustainable enterprise. This article will discuss how to properly handle waste in the production of Shandong pharmaceutical intermediates.First, reasonable classification and storage wasteReasonable classification and storage waste are the first step in waste treatment.