Clonazepam , with the system C15H10ClN3O3 , is a benzodiazepine tranquilizer. Clinically, it is commonly used for: (1) therapy of epilepsy and convulsions, which are advantageous for all kinds of epilepsy, in particular for small seizures and myoclonic seizures. Intravenous therapy of popularity epilepticus. (2) Treatment of anxiousness and insomnia. (3) It is additionally high quality for choreas.
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Clonazepam , with the formula C15H10ClN3O3 , is a benzodiazepine tranquilizer. Clinically, it is mainly used for: (1) treatment of epilepsy and convulsions, which are effective for all types of epilepsy, especially for small seizures and myoclonic seizures. Intravenous treatment of status epilepticus. (2) Treatment of anxiety and insomnia. (3) It is also effective for choreas. It also has a certain effect on drug-induced hyperactivity, chronic multiple convulsions, stiff man syndrome, and various types of neuralgia.The effect is similar to diazepam and nitrazepam.
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Materialized propertiesDensity:1.52±0.1 g/cm3(Predicted)Boiling point:545.3±50.0 °C(Predicted)PSA:80.65000logP:2.52900Acidity coefficient (PKA):11.15±0.70(Predicted)English alias(S)-Methyl 3-(7-bromo-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanoate1H-1,4-Benzodiazepine-3-propanoic acid, 7-bromo-2,3-dihydro-2-oxo-5-(2- pyridinyl)-, methyl ester, (3S)-(3S)-(7-BroMo-2-oxo-5-pyridin-2-yl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-propionic acid Methyl esterMethyl 3-[(3S)-7-bromo-2-oxo-5-(2- pyridinyl)-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateCAS308242-23-1InchiInC
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English alias(S)-Methyl 3-(7-bromo-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanoate1H-1,4-Benzodiazepine-3-propanoic acid, 7-bromo-2,3-dihydro-2-oxo-5-(2- pyridinyl)-, methyl ester, (3S)-(3S)-(7-BroMo-2-oxo-5-pyridin-2-yl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-propionic acid Methyl esterMethyl 3-[(3S)-7-bromo-2-oxo-5-(2- pyridinyl)-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateCAS308242-23-1InchiInChI=1S/C18H16BrN3O3/c1-25-16(23)8-7-15-18(24)22-13-6-5-11(19)10-12(13)17(21-15)14-4-2-3-9-20-14/h2-6,9-10,15H,7-8H2,1H3,(H,22,24)/t15-/m0/s1InChIkeyPITXBYGUVDYTBQ-HNN
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1. Heparin was originally extracted from the liver, and is now mostly extracted from the intestinal mucosa of pigs, sheep, cattle and other animals, and can be extracted from the lungs and liver. Put the fresh intestinal mucosa into the reaction pot, add sodium chloride at 3%, and adjust the pH to 9.5 with 40% sodium hydroxide. Gradually heat up to 60-65 ° C within half an hour, continue to hold heat and stir for 2h, then heat up to 95 ° C, maintain for 10min, cool to below 50 ° C and filter.
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Boiling Point: 143-144 °C35 mm Hg(lit.)Density: 1.568 g/mL at 25 °C(lit.)Refractive index n20/D 1.572(lit.)Flash point > 230 °FSpecific gravity 1.568Sensitivity: Moisture sensitivityBRN4989077CAS DataBase Reference: 86393-34-2use2,4-Dichloro-5-fluorobenzoyl chloride is the main raw material for the preparation of third-generation quinolones such as trifluoroperidinol, trifluoroguabutenyl, pentafluridol and synthetic broad-spectrum antibiotics such as ciprofloxacin, and can also be used for pesticides, insecticides and ovicides, as well as the identification of plastics and resins.synthesisA
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Product Category: Chemical Intermediates - Other Intermediates Cas Number: 21739-92-4Product Specifications: 99% Packing: 25 kg Brand: Runde Detailed Description:5-Bromo-2-chlorobenzoic acidChinese synonyms: 2-Chloro-5-bromobenzoic acid; 5-Bromo-2-chlorobenzoic acid; 5-Bromo-2-chlorobenzoic acid; 5-BroMo-2-chlorobenzoic acid, 98+%; 5-Bromo-2-chlorobenzoic acid; 2-Chloro-5-bromobenzoic acid, 99.86%; 5-Bromo-2-chlorobenzoic acid/2-chloro-5-bromobenzoic acid; 5-BroMo-2-chlorobenzoic acid, 98+%Name: 5-Bromo-2-chlorobenzoic acidEnglish synonyms:Benzoic acid, 5-bromo-2-chloro-; 2-CHLORO-5-BROMOBENZO
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CAS1563-56-0InchiInChI=1S/C12H9BrN2O/c13-8-4-5-10(14)9(7-8)12(16)11-3-1-2-6-15-11/h1-7H,14H2InChIkeyKHVZPFKJBLTYCC-UHFFFAOYSA-NChinese aliasBromazepam Impurity A Bromazepam Impurity A(EP) Standard 2-Amino-5-bromophenyl-2-pyridylmethanone 2-(2-amino-5-bromobenzoyl)pyridineCanonical SmilesC1=CC=NC(=C1)C(=O)C2=C(C=CC(=C2)Br)NInternationalization joint naming(2-amino-5-bromophenyl)-pyridin-2-ylmethanoneEnglish alias2-(5-Bromo-2-aminobenzoyl)pyridine(2-Amino-5-bromophenyl)-2-pyridinylmethanone2-(2-Amino-5-bromobenzoyl)pyridineKetone, 2-amino-5-bromophenyl 2-pyridyl2-Amino-5-bromophenyl-2-pyridylmet
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Method 1Its preparation methods are as follows:2,4-disulfophenol alkali melt hydrolysis method;o-chlorophenol hydrolysis;phenol direct oxidation;phenolic oxidation;O-hydroxycyclohexanone dehydroaromatization.Among them, (1) and (2) the process is complex, the three wastes are polluted, and they are gradually replaced by new processes, while methods (4) and methods (5) are being industrialized abroad.
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Pharmacology and toxicologyWhen the plasma concentration exceeds 5 μg·mL-1, convulsions can occur, and at low doses, it can promote the outflow of K+ in myocardial cells, reduce the auto-discipline of the myocardium, and have anti-ventricular arrhythmic effect; At therapeutic doses, there is no significant effect on the electrical activity of cardiomyocytes, atrioventricular conduction and contraction of myocardium; Further increase in blood concentration can cause slowing of cardiac conduction velocity, atrioventricular block, inhibition of myocardial contractility and decrease of cardiac out
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Pharmacology and toxicologyWhen the plasma awareness exceeds 5 μg·mL-1, convulsions can occur, and at low doses, it can promote the outflow of K+ in myocardial cells, minimize the auto-discipline of the myocardium, and have anti-ventricular arrhythmic effect; At therapeutic doses, there is no full-size impact on the electrical endeavor of cardiomyocytes, atrioventricular conduction and contraction of myocardium; Further enlarge in blood awareness can reason slowing of cardiac conduction velocity, atrioventricular block,
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Psicose is classified as hexose and ketose, and is the differential isomer of D-fructose carbon position 3. IUPAC name (3R,4R,5R)-1,3,4,5, 6-Pentahydroxyhexan-2-one. It has the special function of regulating blood sugar and other beneficial to human health, and is evaluated as the most potential sucrose substitute by the US Food Navigation network.
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Chinese title nitrobenzeneEnglish title nitrobenzeneEnglish aliases moreNitrobenzene physicochemical propertiesDensity 1.205boiling factor 210-211 °C(lit.)melting factor 5-6 °C(lit.)Molecular Formula C6H5NO2Molecular Weight: 123.10900Flash factor one hundred ninety °FExact mass 123.03200PSA 45.82000LogP 2.11800Appearance qualities yellow liquidVapor density 4.2 (vs air)Vapour stress 0.15 mm Hg ( 20 °C)refractive index n20/D 1.551(lit.)Storage conditionsStorage precautions Store in a cool, ventilated warehouse.
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Chinese name nitrobenzeneEnglish name nitrobenzeneEnglish aliases more Nitrobenzene physicochemical propertiesDensity 1.205boiling point 210-211 °C(lit.)melting point 5-6 °C(lit.)Molecular Formula C6H5NO2Molecular Weight: 123.10900Flash point 190 °FExact mass 123.03200PSA 45.82000LogP 2.11800Appearance traits yellow liquidVapor density 4.2 (vs air)Vapour pressure 0.15 mm Hg ( 20 °C)refractive index n20/D 1.551(lit.)Storage conditions Storage precautions Store in a cool, ventilated warehouse. Keep away from tinder, heat sources. Keep the container tightly sealed.
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Salicylic acid, a sort of natural acid, chemical method C7H6O3, is a white crystalline powder, barely soluble in bloodless water, effortlessly soluble in warm water, ethanol, ether and acetone, soluble in warm benzene, commonly used as medicine, spices, dyes, pesticides, rubber components and different essential uncooked substances of great chemicals.1.
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Appearance: yellow or orange-yellow crystalline powder; Odorless and tasteless; It is easy to decompose when exposed to lightMelting point 49-51 °cBoiling Point: 715.32°C (rough estimate)Density0.9145 (rough estimate)refractive index: 1.4760 (estimate)Storage conditions: −20°CSolubility is easily soluble in chloroform.Morphological neatColor: light orange to dark orangeSensitive to photosMerck9843BRN1900141Stable but may be sensitive to light or heat. Store at -20°C protected from light.
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Brief introductionAE-active ester, chemical title 2-methoxyimino-2-(2-amino-4-thiazolyl)-(z)-thioacetic acid benzothiazole ester. Appearance: white or mild yellow crystalline powder, melting factor 128130 °C.
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Basic informationChinese name: AtecaineChinese aliases: aceclofenac impurity H; Methyl 4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylate; [1]English name: Articaine;Methyl (4-methyl-3-(2-(propylamino)propionamido)-2-thiophencarboxylat); 3-(N-propyl-2-amino-propionylamino)-2-carbomethoxy-4-methylthiophene; 4-Methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylic acid,methyl ester; Articaina [INN-Spanish]; Carticaine;Aticaine compound is a white crystalline powder with the formula 4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylate.
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Experimental characteristicsLogP2.47600PSA55.98000Melting point 153-155°CDensity 1.215 Calculate the characteristicsExact molecular weight 198.07900Number of hydrogen bonded donors 1Number of hydrogen bond receptors 3Number of rotatable chemical bonds 2Number of heavy atoms 15Complexity 230Number of isotope atoms 0Determine the number of atomic stereoscopic centers 0The number of atomic stereoscopic centers is uncertain 0Determine the number of chemical bond stereotactic centers 0The number of chemical bond stereotactic centers is uncertain 0Number of covalent bond units 1Hydrophobi
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The appearance is colorless and crystalline, and it can be sublimated when it is exposed to light or discoloration in the air.Appearance trait: colorless crystal. Discoloration in case of air and light. Its solution turns tan in the air.
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Purpose 1Salicylic acid and acetic acid. Slightly soluble in water, soluble in ethanol, ether, chloroform, also soluble in hydroxide alkali solution or carbonic acid solution, and decompose at the same time. Commonly used antipyretic analgesics.
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Sulfadiazine is an natural compound with a molecular formulation of C10H10N4O2S, white or off-white crystals or powders, odorless, tasteless, and step by step darkened when uncovered to light. Almost insoluble in water, soluble in boiling water (1:60), barely soluble in ethanol and acetone, insoluble in chloroform and ether, soluble in dilute hydrochloric acid, sodium hydroxide answer or ammonia solution. Melting factor 252~256 °C (simultaneous decomposition).
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Magnesium sulfate solution, volumetric laxatives and choleretic agents. It is used for catharsis, choleretic, duodenal drainage and nearby swelling.Ingredients BroadcastThe fundamental thing of this product is magnesium sulfate.It is a sterilized aqueous answer of magnesium sulfate. Magnesium sulfate (MgSO4.7H2O) have to be 95.0%~105.0% of the labeled amount.Molecular formula: MgSO4·7H2OMolecular weight: 246.48Indications BroadcastVolumetric laxatives and choleretics.
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