Apixaban Intermediates-manufacture,factory,supplier from China

(Total 24 Products for Apixaban Intermediates)
CAS No. 503615-07-4 Molecular formula C22H22N4O4 molecular weight 406.43EINECS No.
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Purpose 1used as pharmaceutical uncooked materials, fitness care products, intermediates, meals additives, etcPurpose 2D-ribose is an vital issue of nucleic acid, the genetic fabric in residing organisms, which occupies a pivotal function in the metabolism of nucleosides, proteins and fats, and has necessary physiological features and huge software prospects.
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Purpose 1used as pharmaceutical raw materials, health care products, intermediates, food additives, etcPurpose 2D-ribose is an important component of nucleic acid, the genetic material in living organisms, which occupies a pivotal position in the metabolism of nucleosides, proteins and fats, and has important physiological functions and broad application prospects. As a natural component of all cells in living organisms, D-ribose is closely related to the formation of adenylate and the regeneration of ATP, and is one of the most basic sources of energy for life metabolism.
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Product Category: Chemical Intermediates - Other Intermediates Cas Number: 21739-92-4Product Specifications: 99% Packing: 25 kg Brand: Runde Detailed Description:5-Bromo-2-chlorobenzoic acidChinese synonyms: 2-Chloro-5-bromobenzoic acid; 5-Bromo-2-chlorobenzoic acid; 5-Bromo-2-chlorobenzoic acid; 5-BroMo-2-chlorobenzoic acid, 98+%; 5-Bromo-2-chlorobenzoic acid; 2-Chloro-5-bromobenzoic acid, 99.86%; 5-Bromo-2-chlorobenzoic acid/2-chloro-5-bromobenzoic acid; 5-BroMo-2-chlorobenzoic acid, 98+%Name: 5-Bromo-2-chlorobenzoic acidEnglish synonyms:Benzoic acid, 5-bromo-2-chloro-; 2-CHLORO-5-BROMOBENZO
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CAS:21739-92-4Product Category: Chemical Intermediates - Other Intermediates Cas Number: 21739-92-4Product Specifications: 99% Packing: 25 kg Brand: Runde Detailed Description:5-Bromo-2-chlorobenzoic acidChinese synonyms: 2-Chloro-5-bromobenzoic acid; 5-Bromo-2-chlorobenzoic acid; 5-Bromo-2-chlorobenzoic acid; 5-BroMo-2-chlorobenzoic acid, 98+%; 5-Bromo-2-chlorobenzoic acid; 2-Chloro-5-bromobenzoic acid, 99.86%; 5-Bromo-2-chlorobenzoic acid/2-chloro-5-bromobenzoic acid; 5-BroMo-2-chlorobenzoic acid, 98+%Name: 5-Bromo-2-chlorobenzoic acidEnglish synonyms:Benzoic acid, 5-bromo-2-chloro-; 2-CHLOR
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Purpose 1Biochemical studies, adrenocorticosteroid drugs.Purpose 2Glucocorticoids have four major effects: anti-inflammatory, anti-allergic, anti-toxin, and anti-shock.Purpose 3The adrenal cortex secretes the main glucocorticoid, which has three times the anti-inflammatory power of corticosterone.Refer to quality standardsThe content is 96%-104%, mp212-220°C, the specific rotation [α] 20D+161°-+169°, the absorbance coefficient (A) is 428-450, and the content of impurities such as loss on drying and burning residue is detected.
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Magnesium sulfate solution, volumetric laxatives and choleretic agents. It is used for catharsis, choleretic, duodenal drainage and local swelling.Ingredients BroadcastThe main component of this product is magnesium sulfate.It is a sterilized aqueous solution of magnesium sulfate. Magnesium sulfate (MgSO4.7H2O) should be 95.0%~105.0% of the labeled amount.Molecular formula: MgSO4·7H2OMolecular weight: 246.48Indications BroadcastVolumetric laxatives and choleretics.
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Heptoic,acidhexacidc-7,Hexacid, C-7n-heptanoic,heptoicacid,Hepthlic, acidEnanthic, AcidOenanthic, acidEnanthylic acidHeptylic acid1-Hexanecarboxylic acidn-Heptoic acidOenanthylic acidEnanthoic acidNSC 2192n-Heptanoic acidn-Heptylic acidProduction methods and usesmethodGC,NMRHeptanaldehyde is carbonylated from 1-hexene with syngas (CO+H2), and then oxidized by air.Heptanaldehyde is prepared by carbonylation of heptene-1 and syngas, and then heptanoic acid is obtained by air oxidation.
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Formic acid is an organic substance with the chemical formula HCOOH and a molecular weight of 46.03 , commonly known as formic acid, which is the simplest carboxylic acid. A colorless liquid with a pungent odor. Formic acid is a weak electrolyte, but its aqueous solution is weakly acidic and corrosive, which can stimulate skin blistering. It is usually found in the secretions of bees, certain ants, and caterpillars. It is an organic chemical raw material, also used as a disinfectant and preservative.Formic acid was first developed by J. J. -L.
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Formic acid is an natural substance with the chemical system HCOOH and a molecular weight of 46.03 , usually recognized as formic acid, which is the easiest carboxylic acid. A colorless liquid with a pungent odor. Formic acid is a susceptible electrolyte, however its aqueous answer is weakly acidic and corrosive, which can stimulate pores and skin blistering. It is typically determined in the secretions of bees, positive ants, and caterpillars.
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Glycine (Gly), also known as glycine, is a non-essential amino acid with the formula C2H5NO2. Glycine is a constituent amino acid of the endogenous antioxidant reduced glutathione, which is often supplemented exogenously during severe stress in the body, and is sometimes called a semi-essential amino acid. [1] Glycine is one of the simplest amino acids. [4]Solid glycine is a white to off-white crystalline powder, odorless, non-toxic [2]. Soluble in water and almost insoluble in ethanol or ether.
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Guanidine acetate glycine and its derivatives, functional accelerator, does not contain any illegal drugs, no toxic substances, safe to use without discontinuation period.Appearance shape: white or yellowish powder, the carrier will cause the appearance color to change, but does not affect the effect of the product.Mechanism of action Guanidinoacetic acid is a precursor to creatine. Phosphocreatine containing high phosphate group transfer potential energy is widely present in muscle and nerve tissues, and is the main energy supply substance in animal muscle tissues.
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Appearance: Light yellow crystalline powderMelting Point: 128-130 °C(lit.)Boiling Point:563.2±42.0 °C(Predicted)Density 1.63refractive index1.6200 (estimate)Storage conditions: Refrigerator, Under Inert AtmosphereSolubility soluble in chloroform (a little), methanol (a little)pKa1.22±0.10(Predicted)Morphological solidsThe color is pale yellowStability: Moisture sensitiveInChIKeyCOFDRZLHVALCDU-YVLHZVERSA-NCAS DataBase Reference80756-85-0Brief introductionAE-active ester, chemical name 2-methoxyimino-2-(2-amino-4-thiazolyl)-(z)-thioacetic acid benzothiazole ester.
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Pharmacological actionSince the discovery that long-acting local anesthetics can induce cardiac arrest, people have been looking for safer alternatives with less fat solubility. Ropivacaine is such a new long-acting amide local anesthetic, which has a long duration of action and has anesthetic and analgesic effects. Its pharmacological characteristics are low cardiotoxicity, sensory block and motor block are clearly separated, and it has peripheral vasoconstriction effect.
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Trehalose, additionally recognized as fenose and fungose, is a non-reducing disaccharide composed of two glucose molecules with the molecular system C12H22O11 [8].
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Phentermine (Phentermine), an organic compound with a molecular formula of C10H15N, is clinically used as an anorexia (diet drug) for the short-term treatment of moderate to severe obesity, and is listed as a Class II psychotropic drug controlBasic informationChinese name: phentermineEnglish name: phentermineMolecular structure dataMolar refractive index: 48.56Molar volume (cm3/mol): 158.9Isotonic specific volume (90.2K): 387.5Surface tension (dyne/cm): 35.3Polarizability (10-24cm3): 19.25 [5]Flash point: 93.1ºCRefractive index: 1.523Vapour pressure: 0.243mmHg at 25°C CAS number: 122-09-8
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Chinese name Ethyl trifluoroacetoacetateEnglish name Ethyl 4,4,4-trifluoroacetoacetateChinese alias ethyl 4,4,4-trifluoroacetoacetate | 4,4,4-TrifluoroacetylEnglish aliases more Ethyl trifluoroacetoacetate physicochemical propertiesDensity 1.3±0.1 g/cm3boiling point 129.5±0.0 °C at 760 mmHgMelting point -39 °CMolecular Formula C6H7F3O3Molecular weight 184.113flash point 28.9±0.0 °CExact Mass 184.034729Chinese name Ethyl trifluoroacetoacetateEnglish name Ethyl 4,4,4-trifluoroacetoacetateChinese alias ethyl 4,4,4-trifluoroacetoacetate | 4,4,4-TrifluoroacetylWear antistatic overalls and rubb
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Appearance: white or off-white crystalline powder, odorless, bitter taste. Deterioration in contact with light. Mp214-220°C (decomposition); Specific rotation [α] 25D+157.5° (dioxane), +176° (chloroform), +162°-+169° (ethanol); The ethanol solution has a maximum absorption at a wavelength of 242 nm. This product is insoluble in water, insoluble in ether, slightly soluble in chloroform, soluble in acetone, ethanol. Soluble in concentrated sulfuric acid solution and green fluorescence.
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Aspartic acid, also known as aspartic acid, is a α-amino acid, the L-isomer of aspartic acid is one of the 20 protein amino acids, that is, the building unit of protein, its codons are GAU and GAC. It is an acidic amino acid with glutamic acid. It belongs to one of the non-essential amino acids in the human body. Aspartic acid is ubiquitous in biosynthesis. It is a synthetic precursor of amino acids such as lysine, threonine, isoleucine, methionine and purine and pyrimidine bases in living organisms.
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Fields of applicationPurpose 1It is suitable for vitamin B1 deficiency, has the function of maintaining normal glucose metabolism and nerve conduction, and is also used for the adjuvant treatment of dyspepsia and neuritisPreparation method:Method 1Thiamine hydrochloride is usually obtained by condensation, hydrolysis, neutralization, oxidation, and acidification of excess acetamidine hydrochloride with α-dimethoxy β-methoxypropionitrile.Upstream and downstream product informationUpstream raw materialsEthanol, hydrogen peroxide, dimethyl sulfate, ethyl chlorosulfonate, acrylonitrile, carboxylat
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Boiling Point: 143-144 °C35 mm Hg(lit.)Density: 1.568 g/mL at 25 °C(lit.)Refractive index n20/D 1.572(lit.)Flash point > 230 °FSpecific gravity 1.568Sensitivity: Moisture sensitivityBRN4989077CAS DataBase Reference: 86393-34-2use2,4-Dichloro-5-fluorobenzoyl chloride is the main raw material for the preparation of third-generation quinolones such as trifluoroperidinol, trifluoroguabutenyl, pentafluridol and synthetic broad-spectrum antibiotics such as ciprofloxacin, and can also be used for pesticides, insecticides and ovicides, as well as the identification of plastics and resins.synthesisA
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Basic informationChemical formula: C4H4O4Molecular Weight: 116.072CAS number: 110-17-8EINECS number: 203-743-0Physical and chemical propertiesPhysicalDensity: 1.63g/cm3Melting point: 298-300°CBoiling point: 355.5 °cFlash point: 183 °cRefractive index: 1.526(20°C)Appearance: white powder or colorless crystalsSolubility: soluble in ethanol, slightly soluble in water and ether, insoluble in chloroform, carbon tetrachloride, benzeneChemical propertiesThe simplest unsaturated dicarboxylic acid. First found in fusso, it is also found in many kinds of mushrooms and fresh beef.
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Chinese name: tripropylene glycolEnglish name: Tripropylene glycolAlias: H[OC2H3(CH3)]3OHEnglish synonyms: Tripropylenglycol; TRI(PROPYLENE GLYCOL); Tripropyleneglycol,90%; Tripropylene glycol 97%; Tripropylene Glycol Twothe three glycol reduction; Tripropylene Glycol(isomer mix.); 1,1'-(Propylenedioxy)dipropan-2-ol; tripropyleneglycol,mixtureofisomers; [(methylethylene)bis(oxy)]dipropanolChinese Name: Tripropylene glycolChinese synonyms: tripropylene; Diols; Dipropylene glycol; Tris(propylene glycol); trimer 1,2-propanediol; Tripropylene glycol (mixture of isomers); Dipropylene glycol (mi
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Chinese name: tripropylene glycolEnglish name: Tripropylene glycolAlias: H[OC2H3(CH3)]3OHEnglish synonyms: Tripropylenglycol; TRI(PROPYLENE GLYCOL); Tripropyleneglycol,90%; Tripropylene glycol 97%; Tripropylene Glycol Twothe three glycol reduction; Tripropylene Glycol(isomer mix.); 1,1'-(Propylenedioxy)dipropan-2-ol; tripropyleneglycol,mixtureofisomers; [(methylethylene)bis(oxy)]dipropanolChinese Name: Tripropylene glycolChinese synonyms: tripropylene; Diols; Dipropylene glycol; Tris(propylene glycol); trimer 1,2-propanediol; Tripropylene glycol (mixture of isomers); Dipropylene glycol (mi
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Medicine intermediate refers to a compound generated as an intermediate step in the process of synthetic drugs. It has high purity and activity, which can synthesize target drugs through further chemical reactions. Medicine intermediates are widely used in the pharmaceutical industry, covering multiple fields. The classification of pharmaceutical intermediates and its application areas will be introduced below.1. Carboxylic acid intermediate:The intermediate of the carboxylic acid refers to the compound of the carboxylic acid group, and the common ones are benzoic acid and propylic acid.
I. Overview of chemical and pharmaceutical intermediatesChemical pharmaceutical intermediates are a very important part of the pharmaceutical industry, referring to raw materials or semi-finished products in the pharmaceutical industry. These substances undergo a series of chemical reactions to eventually form pharmaceutical products. These chemicals usually exist in liquid or solid form and belong to various types of organic compounds such as acids, alcohols, carboxylic acids, phenols, cork and so on.
April 23, 2020. Customized in the middle of Shandong Pharmaceutical. The so -called Shandong pharmaceutical intermediate is actually some chemical raw materials or chemical products for drug synthesis process. This kind of chemical product does not require the production license of drugs. It can be produced in ordinary chemical plants. As long as it reaches some levels, it can be used for the synthesis of drugs.There are more than 2,000 raw materials and intermediates that need to be matched with chemicals each year, with more than 2.5 million tons.
May 13, 2020. Pharmaceutical intermediate body fluorine customized. Pharmaceutical fluorine: colorless liquid. The melting point -42 ℃. Boiling point 85 ° C. Refractive index (ND20) 1.4650. Relators (D420) 1.024. Insuvenate in water and mixes with ethanol, ether, acetone, and benzene. Apineine reacts through Schiemann (G. Schiemann).Ah. After the aniline was descended to -8 ° C after 31%hydrochloride, and the sodium nitrite solution was nitroded.
Intermediate production of chemical medicine is a work involving a large number of chemicals. If it is not managed and controlled correctly, it may bring serious risks and pollution to the environment. In order to reduce environmental risks in the production of chemical medicine, we need to improve and control from the following aspects.First, establish a scientific and standardized production process. The production of chemical medicine needs to go through multiple steps and reactions. Each step needs to carefully evaluate and formulate corresponding operating procedures.
Shandong is one of the important pharmaceutical production bases in the country, and the production production is relatively concentrated. The treatment of Shandong Pharmaceutical Intermediate waste is essential for protecting the environment, human health, and sustainable enterprise. This article will discuss how to properly handle waste in the production of Shandong pharmaceutical intermediates.First, reasonable classification and storage wasteReasonable classification and storage waste are the first step in waste treatment.