4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile-manufacture,factory,supplier from China

(Total 24 Products for 4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile)
Chinese Name: 2-[(6-chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidine]methyl]butyronitrileEnglish name 2-((6-Chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrileChinese alias alogliptin-B | 2-[(6-Chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]benzonitrile | Alogliptin intermediate | Alogliptin benzoate intermediate 1English aliases more Physicochemical propertiesDensity 1.4±0.1 g/cm3boiling point 418.0±55.0 °C at 760 mmHgMolecular formula C13H10ClN3O2Molecular Weight: 275.690flash point 206.6±31.5 °CExact Mass 275.046143PSA67.79000LogP1.95Vapour
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Chinese Name: 2-[(6-chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidine]methyl]butyronitrileEnglish title 2-((6-Chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrileChinese alias alogliptin-B | 2-[(6-Chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]benzonitrile | Alogliptin intermediate | Alogliptin benzoate intermediate 1English aliases morePhysicochemical propertiesDensity 1.4±0.1 g/cm3boiling factor 418.0±55.0 °C at 760 mmHgMolecular formulation C13H10ClN3O2Molecular Weight: 275.690flash factor 206.6±31.5 °CExact
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Chinese alias-[[2'-(2,5-Dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylic acid (5-Methyl(R)-2-[[2,4-Dioxo-3-methyl-6-(3-amino-1-piperidinyl)-1,2,3,4-tetrahydro-1-pyrimidinyl]methyl]-4- Flubenzonitrile succinate succinate tragliptin 2 tropagliptin succinate succinate tradagliptin succinate 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-4-fluorobenzonitrile succinateEnglish aliasSYR111472 SuccinateSuccinic acid - 2-({6-[(3R)-3-amino-1-piperidinyl]-3-methyl-2,4-dioxo-3,4-dihydro-1(2H)-pyrimid
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Storage Conditions/Storage methods:Seal away from light and store in a cool place.Stability related:Other information:1. Properties: White or white powder. Almost odorless, tasteless and hygroscopic.2. Solubility: soluble in water and salt water, insoluble in ethanol, acetone, benzene, chloroform and ether. The pH of 1% aqueous solution is 6.0~7.5.Heparin was originally extracted from the liver, and is now mostly extracted from the intestinal mucosa of pigs, sheep, cattle and other animals, and can be extracted from the lungs and liver.
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Basic informationChinese name: AtecaineChinese aliases: aceclofenac impurity H; Methyl 4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylate; [1]English name: Articaine;Methyl (4-methyl-3-(2-(propylamino)propionamido)-2-thiophencarboxylat); 3-(N-propyl-2-amino-propionylamino)-2-carbomethoxy-4-methylthiophene; 4-Methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylic acid,methyl ester; Articaina [INN-Spanish]; Carticaine;Aticaine compound is a white crystalline powder with the components 4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylate.
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Materialized propertiesDensity:1.52±0.1 g/cm3(Predicted)Boiling point:545.3±50.0 °C(Predicted)PSA:80.65000logP:2.52900Acidity coefficient (PKA):11.15±0.70(Predicted)English alias(S)-Methyl 3-(7-bromo-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanoate1H-1,4-Benzodiazepine-3-propanoic acid, 7-bromo-2,3-dihydro-2-oxo-5-(2- pyridinyl)-, methyl ester, (3S)-(3S)-(7-BroMo-2-oxo-5-pyridin-2-yl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-propionic acid Methyl esterMethyl 3-[(3S)-7-bromo-2-oxo-5-(2- pyridinyl)-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateCAS308242-23-1InchiInC
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English alias(S)-Methyl 3-(7-bromo-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanoate1H-1,4-Benzodiazepine-3-propanoic acid, 7-bromo-2,3-dihydro-2-oxo-5-(2- pyridinyl)-, methyl ester, (3S)-(3S)-(7-BroMo-2-oxo-5-pyridin-2-yl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-propionic acid Methyl esterMethyl 3-[(3S)-7-bromo-2-oxo-5-(2- pyridinyl)-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateCAS308242-23-1InchiInChI=1S/C18H16BrN3O3/c1-25-16(23)8-7-15-18(24)22-13-6-5-11(19)10-12(13)17(21-15)14-4-2-3-9-20-14/h2-6,9-10,15H,7-8H2,1H3,(H,22,24)/t15-/m0/s1InChIkeyPITXBYGUVDYTBQ-HNN
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Basic informationChinese name: AtecaineChinese aliases: aceclofenac impurity H; Methyl 4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylate; [1]English name: Articaine;Methyl (4-methyl-3-(2-(propylamino)propionamido)-2-thiophencarboxylat); 3-(N-propyl-2-amino-propionylamino)-2-carbomethoxy-4-methylthiophene; 4-Methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylic acid,methyl ester; Articaina [INN-Spanish]; Carticaine;Aticaine compound is a white crystalline powder with the formula 4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylate.
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1. Heparin was originally extracted from the liver, and is now mostly extracted from the intestinal mucosa of pigs, sheep, cattle and other animals, and can be extracted from the lungs and liver. Put the fresh intestinal mucosa into the reaction pot, add sodium chloride at 3%, and adjust the pH to 9.5 with 40% sodium hydroxide. Gradually heat up to 60-65 ° C within half an hour, continue to hold heat and stir for 2h, then heat up to 95 ° C, maintain for 10min, cool to below 50 ° C and filter.
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apply4-chloropyridine hydrochloride is an important intermediate in organic synthesis, which is widely used in the preparation of new medicines, pesticides, dyes, etc.use4-Chloropyridine hydrochloride can be used as a pharmaceutical intermediate in the process of laboratory organic synthesis and chemical and pharmaceutical research and development, and pyridine base can be used to synthesize more than 50 drugs, including antitumor drugs, penicillin, vasodilators, nicotinate, inositol nicotinate, etc.preparationPyridine is used as the starting material, and 4-chloropyridine hydrochloride is syn
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2,3,4,5-TETRAFLUORBENZOYLCHLORID2,3,4,5-TETRAFLUOROBENZOYL CHLORIDEBenzoyl chloride, 2,3,4,5-tetrafluoro- (9CI)2,3,4,5-Tetrafluorobenzoyl2,3,4,5-Tetrafluorobenzoyl chloride 98%2,3,4,5-TETRAFLUOROBEZOYL CHLORIDE2,3,4,5-Tetrafluorobenzoylchloride98%94-24-62,3,4,5-Tetrafluorobenzoic acid chlorideBoiling point 65-66 °C 10mmDensity: 1.58 g/mL at 25 °C(lit.)Refractive index n20/D 1.4787(lit.)Flash point 194 °FSpecific gravity 1.580Sensitivity: Moisture sensitivityBRN5266860InChIKeyXWCKIXLTBNGIHV-UHFFFAOYSA-NCAS DataBase Reference94695-48-4
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Chinese name: 1-[[2-(4-chlorophenyl)ethyl]amino]-2-chloropropane hydrochloride Chinese synonymous with green casserin intermediate; Lorcaserin intermediate 2; Lorcaserin Impurity B; 1-[[2-(4-chlorophenyl)ethyl]amino]-2-chloropropane hydrochloride; Lorcaserin hydrochloride intermediate 2; 2-Chloro-N-(4-chlorophenethyl)propan-1-amine chloride; Lorcaserin impurity B (EP); Chlorocasein Impurity B English name 1-[[2-(4-Chlorophenyl)ethyl]amino]-2-chloropropane English synonym 1-[[2-(4-Chlorophenyl)ethyl]amino]-2-chloropropane; 1-[[2-(4-Chlorophenyl)ethyl]amino]-2-chloropropaneHydrochloride; Benzene
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Chinese Name: Thiopidine trioxide Chinese synonyms: compounds of thiopidine trioxide; sulfur trioxide-pyridine complex; Pyridine sulfur trioxide; Thiopidine trioxide; Thiopidine trioxide complex; Synthesis of thiophorine trioxide; Sulfur trioxide yridine complex; Sulfurtrioxypyridine complex [2]English name: Pyridine sulfur trioxide English synonyms: Pyridine, compd.withsulfurtrioxide (1:1); Salfurtrioxidepyri-dinecomplex; Sulfurtrioxide,compd.withpyridine(1:1); (DIMETHYLAMINOMETHYL) STYRENE; VINYLBENZYLDIMETHYLAMINE; N,N-DIMETHYLVINYLBENZYLAMINE; POLY(4-VINYLPYRIDINE) SULFUR TRIOXID
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Chinese aliaso-Aminobenzonitrile 2-aminobenzonitrile 2-cyanoaniline-o-cyanoaniline 2-aminobenzonitrile 50G2-aminobenzonitrile 2-aminobenzonitrile 2-amino-benzonitrile 2-aminophenylhydrazine 2-aminobenzonitrileEnglish aliasO-AMINOBENZONITRILE2-Aminobenzonitrile, (AnthranilonitrileO-CYANOANILINE2-amino-benzonitrilBenzonitrile,  o-amino-Aminobenzonitrile2-Cyano-1-aminobenzene2-amino-benzonitrile1-amino-2-cyanobenzene2-CyanoanilineEINECS 217-549-92- cyano-anilineAnthranilonitrileortho-cyanoaniline2-AminobenzolcarbonitrilBenzonitrile, 2-amino-amino benzonitrileBenzonitrile,2-amino2-Amino Benzo
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Method 1Its preparation methods are as follows:2,4-disulfophenol alkali melt hydrolysis method;o-chlorophenol hydrolysis;phenol direct oxidation;phenolic oxidation;O-hydroxycyclohexanone dehydroaromatization.Among them, (1) and (2) the process is complex, the three wastes are polluted, and they are gradually replaced by new processes, while methods (4) and methods (5) are being industrialized abroad.
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n-propanol, also known as 1-propanol, is an organic compound with a simple structural formula of CH3CH2CH2OH, a molecular formula of C3H8O, and a molecular weight of 60.10. At room temperature and pressure, n-propanol is a transparent colorless liquid with a strong musty smell similar to external alcohol, soluble in water, ethanol and ether. Generally, propionaldehyde is obtained by the synthesis of ethylene by carbonyl group, and then reduced to obtain.
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Uses: used as solvents, plasticizers, antifreeze, but also used to make flavors and cosmetics.Part I: Chemical NamesChemical Chinese Name: n-octanol; 1-OctanolChemical English name: Octanol; Capryl alcoholChinese common name or trade name:  Synonyms:  CAS No.: 111-87-5Molecular Formula: C8H18OMolecular weight: 130.23Part II: Composition/composition information             Pure chemical mixture             Chemical name: n-octanol; 1-OctanolHazardous Substance Content CAS No.Octanol 100 111-87-5Part III: Overview of
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Imidazole, molecular formulation C3H4N2, is an natural compound, a kind of diazole, a five-membered fragrant heterocyclic compound containing two meta-nitrogen atoms in its molecular structure.
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Brief introductionAE-active ester, chemical title 2-methoxyimino-2-(2-amino-4-thiazolyl)-(z)-thioacetic acid benzothiazole ester. Appearance: white or mild yellow crystalline powder, melting factor 128130 °C.
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Chinese name: 1-[[2-(4-chlorophenyl)ethyl]amino]-2-chloropropane hydrochloride Chinese synonymous with inexperienced casserin intermediate; Lorcaserin intermediate 2; Lorcaserin Impurity B; 1-[[2-(4-chlorophenyl)ethyl]amino]-2-chloropropane hydrochloride; Lorcaserin hydrochloride intermediate 2; 2-Chloro-N-(4-chlorophenethyl)propan-1-amine chloride; Lorcaserin impurity B (EP); Chlorocasein Impurity B English title 1-[[2-(4-Chlorophenyl)ethyl]amino]-2-chloropropane English synonym 1-[[2-(4-Chlorophenyl)ethyl]amino]-2-chloropropane; 1-[[2-(4-Chlorophenyl)ethyl]amino]-2-chloro
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Hydrazine hydrate, also known as hydrazine hydrate, is a colorless and transparent oily liquid with a light ammonia smell, smoke in humid air, and is highly alkaline and hygroscopic.
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CAS:26412-87-3Chinese Name: Thiopidine trioxide Chinese synonyms: compounds of thiopidine trioxide; sulfur trioxide-pyridine complex; Pyridine sulfur trioxide; Thiopidine trioxide; Thiopidine trioxide complex; Synthesis of thiophorine trioxide; Sulfur trioxide yridine complex; Sulfurtrioxypyridine complicated [2]English name: Pyridine sulfur trioxide English synonyms: Pyridine, compd.withsulfurtrioxide (1:1); Salfurtrioxidepyri-dinecomplex; Sulfurtrioxide,compd.withpyridine(1:1); (DIMETHYLAMINOMETHYL) STYRENE; VINYLBENZYLDIMETHYLAMINE; N,N-DIMETHYLVINYLBENZYLAMINE; POLY(4-V
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Character description: colorless transparent liquid. Melting point -90.2C, boiling point 117.7 °C, relative density 0.8098 (20/4C), refractive index 1.3993, flash point 35.35.5 °C, spontaneous ignition point 365 °C. The solubility in water at 20 °C is 7.7% (mass), and the solubility of water in n-butanol is 20.1% (mass). Miscible with ethanol, ethyl and other organic solvents. Vapor forms an explosive mixture with air, with an explosion limit of 1.45-11.25 (volume). It can form an azeotropic mixture with water, its boiling point is 92 °C, and the water content is 37%.
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Sodium gluconate is a kind of organic matter, chemical formula C6H11NaO7, in the industry is very widely used, sodium gluconate can be used in construction, textile printing and dyeing and metal surface treatment and water treatment industries as efficient chelating agent, steel surface cleaning agent, glass bottle cleaning agent, electroplating industrial aluminum oxide coloring, in the concrete industry as a high efficiency retarding agent, high efficiency water reducing agent.Used as a cleaning agent for steel surface:Steel surface such as the need for plating bowl, chromium plating, tin pl
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Medicine intermediate refers to a compound generated as an intermediate step in the process of synthetic drugs. It has high purity and activity, which can synthesize target drugs through further chemical reactions. Medicine intermediates are widely used in the pharmaceutical industry, covering multiple fields. The classification of pharmaceutical intermediates and its application areas will be introduced below.1. Carboxylic acid intermediate:The intermediate of the carboxylic acid refers to the compound of the carboxylic acid group, and the common ones are benzoic acid and propylic acid.
May 13, 2020. Pharmaceutical intermediate body fluorine customized. Pharmaceutical fluorine: colorless liquid. The melting point -42 ℃. Boiling point 85 ° C. Refractive index (ND20) 1.4650. Relators (D420) 1.024. Insuvenate in water and mixes with ethanol, ether, acetone, and benzene. Apineine reacts through Schiemann (G. Schiemann).Ah. After the aniline was descended to -8 ° C after 31%hydrochloride, and the sodium nitrite solution was nitroded.
I. Overview of chemical and pharmaceutical intermediatesChemical pharmaceutical intermediates are a very important part of the pharmaceutical industry, referring to raw materials or semi-finished products in the pharmaceutical industry. These substances undergo a series of chemical reactions to eventually form pharmaceutical products. These chemicals usually exist in liquid or solid form and belong to various types of organic compounds such as acids, alcohols, carboxylic acids, phenols, cork and so on.
Intermediate production of chemical medicine is a work involving a large number of chemicals. If it is not managed and controlled correctly, it may bring serious risks and pollution to the environment. In order to reduce environmental risks in the production of chemical medicine, we need to improve and control from the following aspects.First, establish a scientific and standardized production process. The production of chemical medicine needs to go through multiple steps and reactions. Each step needs to carefully evaluate and formulate corresponding operating procedures.
April 23, 2020. Customized in the middle of Shandong Pharmaceutical. The so -called Shandong pharmaceutical intermediate is actually some chemical raw materials or chemical products for drug synthesis process. This kind of chemical product does not require the production license of drugs. It can be produced in ordinary chemical plants. As long as it reaches some levels, it can be used for the synthesis of drugs.There are more than 2,000 raw materials and intermediates that need to be matched with chemicals each year, with more than 2.5 million tons.
Shandong is one of the important pharmaceutical production bases in the country, and the production production is relatively concentrated. The treatment of Shandong Pharmaceutical Intermediate waste is essential for protecting the environment, human health, and sustainable enterprise. This article will discuss how to properly handle waste in the production of Shandong pharmaceutical intermediates.First, reasonable classification and storage wasteReasonable classification and storage waste are the first step in waste treatment.