apply4-chloropyridine hydrochloride is an important intermediate in organic synthesis, which is widely used in the preparation of new medicines, pesticides, dyes, etc.use4-Chloropyridine hydrochloride can be used as a pharmaceutical intermediate in the process of laboratory organic synthesis and chemical and pharmaceutical research and development, and pyridine base can be used to synthesize more than 50 drugs, including antitumor drugs, penicillin, vasodilators, nicotinate, inositol nicotinate, etc.preparationPyridine is used as the starting material, and 4-chloropyridine hydrochloride is syn
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2,3,4,5-TETRAFLUORBENZOYLCHLORID2,3,4,5-TETRAFLUOROBENZOYL CHLORIDEBenzoyl chloride, 2,3,4,5-tetrafluoro- (9CI)2,3,4,5-Tetrafluorobenzoyl2,3,4,5-Tetrafluorobenzoyl chloride 98%2,3,4,5-TETRAFLUOROBEZOYL CHLORIDE2,3,4,5-Tetrafluorobenzoylchloride98%94-24-62,3,4,5-Tetrafluorobenzoic acid chlorideBoiling point 65-66 °C 10mmDensity: 1.58 g/mL at 25 °C(lit.)Refractive index n20/D 1.4787(lit.)Flash point 194 °FSpecific gravity 1.580Sensitivity: Moisture sensitivityBRN5266860InChIKeyXWCKIXLTBNGIHV-UHFFFAOYSA-NCAS DataBase Reference94695-48-4
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2,3,4,5-TETRAFLUORBENZOYLCHLORID2,3,4,5-TETRAFLUOROBENZOYL CHLORIDEBenzoyl chloride, 2,3,4,5-tetrafluoro- (9CI)2,3,4,5-Tetrafluorobenzoyl2,3,4,5-Tetrafluorobenzoyl chloride 98%2,3,4,5-TETRAFLUOROBEZOYL CHLORIDE2,3,4,5-Tetrafluorobenzoylchloride98%94-24-62,3,4,5-Tetrafluorobenzoic acid chlorideBoiling point 65-66 °C 10mmDensity: 1.58 g/mL at 25 °C(lit.)Refractive index n20/D 1.4787(lit.)Flash point 194 °FSpecific gravity 1.580Sensitivity: Moisture sensitivityBRN5266860InChIKeyXWCKIXLTBNGIHV-UHFFFAOYSA-NCAS DataBase Reference94695-48-4
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Fields of applicationPurpose 1It is suitable for vitamin B1 deficiency, has the function of maintaining normal glucose metabolism and nerve conduction, and is also used for the adjuvant treatment of dyspepsia and neuritisPreparation method:Method 1Thiamine hydrochloride is usually obtained by condensation, hydrolysis, neutralization, oxidation, and acidification of excess acetamidine hydrochloride with α-dimethoxy β-methoxypropionitrile.Upstream and downstream product informationUpstream raw materialsEthanol, hydrogen peroxide, dimethyl sulfate, ethyl chlorosulfonate, acrylonitrile, carboxylat
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Boiling Point: 143-144 °C35 mm Hg(lit.)Density: 1.568 g/mL at 25 °C(lit.)Refractive index n20/D 1.572(lit.)Flash point > 230 °FSpecific gravity 1.568Sensitivity: Moisture sensitivityBRN4989077CAS DataBase Reference: 86393-34-2use2,4-Dichloro-5-fluorobenzoyl chloride is the main raw material for the preparation of third-generation quinolones such as trifluoroperidinol, trifluoroguabutenyl, pentafluridol and synthetic broad-spectrum antibiotics such as ciprofloxacin, and can also be used for pesticides, insecticides and ovicides, as well as the identification of plastics and resins.synthesisA
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Chinese name: 1-[[2-(4-chlorophenyl)ethyl]amino]-2-chloropropane hydrochloride Chinese synonymous with green casserin intermediate; Lorcaserin intermediate 2; Lorcaserin Impurity B; 1-[[2-(4-chlorophenyl)ethyl]amino]-2-chloropropane hydrochloride; Lorcaserin hydrochloride intermediate 2; 2-Chloro-N-(4-chlorophenethyl)propan-1-amine chloride; Lorcaserin impurity B (EP); Chlorocasein Impurity B English name 1-[[2-(4-Chlorophenyl)ethyl]amino]-2-chloropropane English synonym 1-[[2-(4-Chlorophenyl)ethyl]amino]-2-chloropropane; 1-[[2-(4-Chlorophenyl)ethyl]amino]-2-chloropropaneHydrochloride; Benzene
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1. Heparin was originally extracted from the liver, and is now mostly extracted from the intestinal mucosa of pigs, sheep, cattle and other animals, and can be extracted from the lungs and liver. Put the fresh intestinal mucosa into the reaction pot, add sodium chloride at 3%, and adjust the pH to 9.5 with 40% sodium hydroxide. Gradually heat up to 60-65 ° C within half an hour, continue to hold heat and stir for 2h, then heat up to 95 ° C, maintain for 10min, cool to below 50 ° C and filter.
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Chinese name: 1-[[2-(4-chlorophenyl)ethyl]amino]-2-chloropropane hydrochloride Chinese synonymous with inexperienced casserin intermediate; Lorcaserin intermediate 2; Lorcaserin Impurity B; 1-[[2-(4-chlorophenyl)ethyl]amino]-2-chloropropane hydrochloride; Lorcaserin hydrochloride intermediate 2; 2-Chloro-N-(4-chlorophenethyl)propan-1-amine chloride; Lorcaserin impurity B (EP); Chlorocasein Impurity B English title 1-[[2-(4-Chlorophenyl)ethyl]amino]-2-chloropropane English synonym 1-[[2-(4-Chlorophenyl)ethyl]amino]-2-chloropropane; 1-[[2-(4-Chlorophenyl)ethyl]amino]-2-chloro
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Boiling Point: 143-144 °C35 mm Hg(lit.)Density: 1.568 g/mL at 25 °C(lit.)Refractive index n20/D 1.572(lit.)Flash point > 230 °FSpecific gravity 1.568Sensitivity: Moisture sensitivityBRN4989077CAS DataBase Reference: 86393-34-2use2,4-Dichloro-5-fluorobenzoyl chloride is the main raw material for the preparation of third-generation quinolones such as trifluoroperidinol, trifluoroguabutenyl, pentafluridol and synthetic broad-spectrum antibiotics such as ciprofloxacin, and can also be used for pesticides, insecticides and ovicides, as well as the identification of plastics and resins.synthesisA
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Brief introductionAE-active ester, chemical title 2-methoxyimino-2-(2-amino-4-thiazolyl)-(z)-thioacetic acid benzothiazole ester. Appearance: white or mild yellow crystalline powder, melting factor 128130 °C.
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Imidazole, molecular formulation C3H4N2, is an natural compound, a kind of diazole, a five-membered fragrant heterocyclic compound containing two meta-nitrogen atoms in its molecular structure.
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Hydrazine hydrate, also known as hydrazine hydrate, is a colorless and transparent oily liquid with a light ammonia smell, smoke in humid air, and is highly alkaline and hygroscopic.
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Chinese Name: Trogliptin succinateChinese aliases: trogliptin 2CAS No:1029877-94-8Molecular Formula: C22H26FN5O6Appearance white to beige solidUses: Using DPP-4 taken from Caco-2 cells as a material, the IC50 of trogliptin was measured to be 5.4nmol/L; Using the plasma DPP-4 of humans, dogs and rats as materials, the IC50s of tradagliptin were measured to be 4.2 nmol/L, 6.2 nmol/L and 9.7 nmol/L, respectively.
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Appearance: Colorless liquid. The boiling point is 189 °C, the relative density is 1.073 (25/4 °C), the refractive index is 1.4494, and the flash point is 76 °C. Soluble in organic solvents, insoluble in water.Melting point -52 °cBoiling Point: 189 °C(lit.)Density 1.075 g/mL at 20 °CVapor pressure 4.2hPa at 25°CRefractive index n20/D 1.449(lit.)Flash point 169 °FStorage conditions RefrigeratorMorphological liquidThe color is transparentWater solubility: 0.5-1.0 g/100 mL at 20 ºCBRN2506Stability is unstable. Sensitivity to light. MEHQ of about 100 ppm can be used as a stabilizer.
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Method 1Its preparation methods are as follows:2,4-disulfophenol alkali melt hydrolysis method;o-chlorophenol hydrolysis;phenol direct oxidation;phenolic oxidation;O-hydroxycyclohexanone dehydroaromatization.Among them, (1) and (2) the process is complex, the three wastes are polluted, and they are gradually replaced by new processes, while methods (4) and methods (5) are being industrialized abroad.
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Appearance: White crystalline.Melting Point: 210 °C (subl.) (lit.)Flash point 198 °CStorage conditionsKeep in dark place,Inert atmosphere,Room temperatureMorphological crystalline powderColor: off-white to yellowish-beigePH 2.0 (100g/l, H2O, 20°C)Water solubility is easily soluble in water.Detection Method: HPLCBRN3684904InChIKeyXGAFCCUNHIMIRV-UHFFFAOYSA-NCAS DataBase Reference7379-35-3EPA Chemical Substance Information 4-Chloropyridine hydrochloride (7379-35-3)apply4-chloropyridine hydrochloride is an important intermediate in organic synthesis, which is widely used in the preparation of new
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Appearance: Light yellow crystalline powderMelting Point: 128-130 °C(lit.)Boiling Point:563.2±42.0 °C(Predicted)Density 1.63refractive index1.6200 (estimate)Storage conditions: Refrigerator, Under Inert AtmosphereSolubility soluble in chloroform (a little), methanol (a little)pKa1.22±0.10(Predicted)Morphological solidsThe color is pale yellowStability: Moisture sensitiveInChIKeyCOFDRZLHVALCDU-YVLHZVERSA-NCAS DataBase Reference80756-85-0Brief introductionAE-active ester, chemical name 2-methoxyimino-2-(2-amino-4-thiazolyl)-(z)-thioacetic acid benzothiazole ester.
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Basic informationChinese name: AtecaineChinese aliases: aceclofenac impurity H; Methyl 4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylate; [1]English name: Articaine;Methyl (4-methyl-3-(2-(propylamino)propionamido)-2-thiophencarboxylat); 3-(N-propyl-2-amino-propionylamino)-2-carbomethoxy-4-methylthiophene; 4-Methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylic acid,methyl ester; Articaina [INN-Spanish]; Carticaine;Aticaine compound is a white crystalline powder with the formula 4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylate.
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Chinese Name: Thiopidine trioxide Chinese synonyms: compounds of thiopidine trioxide; sulfur trioxide-pyridine complex; Pyridine sulfur trioxide; Thiopidine trioxide; Thiopidine trioxide complex; Synthesis of thiophorine trioxide; Sulfur trioxide yridine complex; Sulfurtrioxypyridine complex [2]English name: Pyridine sulfur trioxide English synonyms: Pyridine, compd.withsulfurtrioxide (1:1); Salfurtrioxidepyri-dinecomplex; Sulfurtrioxide,compd.withpyridine(1:1); (DIMETHYLAMINOMETHYL) STYRENE; VINYLBENZYLDIMETHYLAMINE; N,N-DIMETHYLVINYLBENZYLAMINE; POLY(4-VINYLPYRIDINE) SULFUR TRIOXID
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Appearance: Colorless liquid. The boiling point is 189 °C, the relative density is 1.073 (25/4 °C), the refractive index is 1.4494, and the flash point is 76 °C. Soluble in organic solvents, insoluble in water.Melting point -52 °cBoiling Point: 189 °C(lit.)Density 1.075 g/mL at 20 °CVapor pressure 4.2hPa at 25°CRefractive index n20/D 1.449(lit.)Flash point 169 °FStorage conditions RefrigeratorMorphological liquidThe color is transparentWater solubility: 0.5-1.0 g/100 mL at 20 ºCBRN2506Stability is unstable. Sensitivity to light. MEHQ of about 100 ppm can be used as a stabilizer.
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Basic informationChinese name: AtecaineChinese aliases: aceclofenac impurity H; Methyl 4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylate; [1]English name: Articaine;Methyl (4-methyl-3-(2-(propylamino)propionamido)-2-thiophencarboxylat); 3-(N-propyl-2-amino-propionylamino)-2-carbomethoxy-4-methylthiophene; 4-Methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylic acid,methyl ester; Articaina [INN-Spanish]; Carticaine;Aticaine compound is a white crystalline powder with the components 4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylate.
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CAS No. 503615-07-4 Molecular formula C22H22N4O4 molecular weight 406.43EINECS No.
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CAS No. 503615-07-4Molecular components C22H22N4O4 molecular weight 406.43EINECS No.
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Appearance: Yellow needle-like crystals.
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