Boiling Point: 143-144 °C35 mm Hg(lit.)Density: 1.568 g/mL at 25 °C(lit.)Refractive index n20/D 1.572(lit.)Flash point > 230 °FSpecific gravity 1.568Sensitivity: Moisture sensitivityBRN4989077CAS DataBase Reference: 86393-34-2use2,4-Dichloro-5-fluorobenzoyl chloride is the main raw material for the preparation of third-generation quinolones such as trifluoroperidinol, trifluoroguabutenyl, pentafluridol and synthetic broad-spectrum antibiotics such as ciprofloxacin, and can also be used for pesticides, insecticides and ovicides, as well as the identification of plastics and resins.synthesisA
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Boiling Point: 143-144 °C35 mm Hg(lit.)Density: 1.568 g/mL at 25 °C(lit.)Refractive index n20/D 1.572(lit.)Flash point > 230 °FSpecific gravity 1.568Sensitivity: Moisture sensitivityBRN4989077CAS DataBase Reference: 86393-34-2use2,4-Dichloro-5-fluorobenzoyl chloride is the main raw material for the preparation of third-generation quinolones such as trifluoroperidinol, trifluoroguabutenyl, pentafluridol and synthetic broad-spectrum antibiotics such as ciprofloxacin, and can also be used for pesticides, insecticides and ovicides, as well as the identification of plastics and resins.synthesisA
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2,3,4,5-TETRAFLUORBENZOYLCHLORID2,3,4,5-TETRAFLUOROBENZOYL CHLORIDEBenzoyl chloride, 2,3,4,5-tetrafluoro- (9CI)2,3,4,5-Tetrafluorobenzoyl2,3,4,5-Tetrafluorobenzoyl chloride 98%2,3,4,5-TETRAFLUOROBEZOYL CHLORIDE2,3,4,5-Tetrafluorobenzoylchloride98%94-24-62,3,4,5-Tetrafluorobenzoic acid chlorideBoiling point 65-66 °C 10mmDensity: 1.58 g/mL at 25 °C(lit.)Refractive index n20/D 1.4787(lit.)Flash point 194 °FSpecific gravity 1.580Sensitivity: Moisture sensitivityBRN5266860InChIKeyXWCKIXLTBNGIHV-UHFFFAOYSA-NCAS DataBase Reference94695-48-4
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Fields of applicationPurpose 1It is suitable for vitamin B1 deficiency, has the function of maintaining normal glucose metabolism and nerve conduction, and is also used for the adjuvant treatment of dyspepsia and neuritisPreparation method:Method 1Thiamine hydrochloride is usually obtained by condensation, hydrolysis, neutralization, oxidation, and acidification of excess acetamidine hydrochloride with α-dimethoxy β-methoxypropionitrile.Upstream and downstream product informationUpstream raw materialsEthanol, hydrogen peroxide, dimethyl sulfate, ethyl chlorosulfonate, acrylonitrile, carboxylat
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Method 1Its preparation methods are as follows:2,4-disulfophenol alkali melt hydrolysis method;o-chlorophenol hydrolysis;phenol direct oxidation;phenolic oxidation;O-hydroxycyclohexanone dehydroaromatization.Among them, (1) and (2) the process is complex, the three wastes are polluted, and they are gradually replaced by new processes, while methods (4) and methods (5) are being industrialized abroad.
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apply4-chloropyridine hydrochloride is an important intermediate in organic synthesis, which is widely used in the preparation of new medicines, pesticides, dyes, etc.use4-Chloropyridine hydrochloride can be used as a pharmaceutical intermediate in the process of laboratory organic synthesis and chemical and pharmaceutical research and development, and pyridine base can be used to synthesize more than 50 drugs, including antitumor drugs, penicillin, vasodilators, nicotinate, inositol nicotinate, etc.preparationPyridine is used as the starting material, and 4-chloropyridine hydrochloride is syn
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2,3,4,5-TETRAFLUORBENZOYLCHLORID2,3,4,5-TETRAFLUOROBENZOYL CHLORIDEBenzoyl chloride, 2,3,4,5-tetrafluoro- (9CI)2,3,4,5-Tetrafluorobenzoyl2,3,4,5-Tetrafluorobenzoyl chloride 98%2,3,4,5-TETRAFLUOROBEZOYL CHLORIDE2,3,4,5-Tetrafluorobenzoylchloride98%94-24-62,3,4,5-Tetrafluorobenzoic acid chlorideBoiling point 65-66 °C 10mmDensity: 1.58 g/mL at 25 °C(lit.)Refractive index n20/D 1.4787(lit.)Flash point 194 °FSpecific gravity 1.580Sensitivity: Moisture sensitivityBRN5266860InChIKeyXWCKIXLTBNGIHV-UHFFFAOYSA-NCAS DataBase Reference94695-48-4
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Chinese alias-[[2'-(2,5-Dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylic acid (5-Methyl(R)-2-[[2,4-Dioxo-3-methyl-6-(3-amino-1-piperidinyl)-1,2,3,4-tetrahydro-1-pyrimidinyl]methyl]-4- Flubenzonitrile succinate succinate tragliptin 2 tropagliptin succinate succinate tradagliptin succinate 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-4-fluorobenzonitrile succinateEnglish aliasSYR111472 SuccinateSuccinic acid - 2-({6-[(3R)-3-amino-1-piperidinyl]-3-methyl-2,4-dioxo-3,4-dihydro-1(2H)-pyrimid
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1. Heparin was originally extracted from the liver, and is now mostly extracted from the intestinal mucosa of pigs, sheep, cattle and other animals, and can be extracted from the lungs and liver. Put the fresh intestinal mucosa into the reaction pot, add sodium chloride at 3%, and adjust the pH to 9.5 with 40% sodium hydroxide. Gradually heat up to 60-65 ° C within half an hour, continue to hold heat and stir for 2h, then heat up to 95 ° C, maintain for 10min, cool to below 50 ° C and filter.
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Chinese Name: 2-[(6-chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidine]methyl]butyronitrileEnglish name 2-((6-Chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrileChinese alias alogliptin-B | 2-[(6-Chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]benzonitrile | Alogliptin intermediate | Alogliptin benzoate intermediate 1English aliases more Physicochemical propertiesDensity 1.4±0.1 g/cm3boiling point 418.0±55.0 °C at 760 mmHgMolecular formula C13H10ClN3O2Molecular Weight: 275.690flash point 206.6±31.5 °CExact Mass 275.046143PSA67.79000LogP1.95Vapour
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Product Category: Chemical Intermediates - Other Intermediates Cas Number: 21739-92-4Product Specifications: 99% Packing: 25 kg Brand: Runde Detailed Description:5-Bromo-2-chlorobenzoic acidChinese synonyms: 2-Chloro-5-bromobenzoic acid; 5-Bromo-2-chlorobenzoic acid; 5-Bromo-2-chlorobenzoic acid; 5-BroMo-2-chlorobenzoic acid, 98+%; 5-Bromo-2-chlorobenzoic acid; 2-Chloro-5-bromobenzoic acid, 99.86%; 5-Bromo-2-chlorobenzoic acid/2-chloro-5-bromobenzoic acid; 5-BroMo-2-chlorobenzoic acid, 98+%Name: 5-Bromo-2-chlorobenzoic acidEnglish synonyms:Benzoic acid, 5-bromo-2-chloro-; 2-CHLORO-5-BROMOBENZO
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Chinese Name: 2-[(6-chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidine]methyl]butyronitrileEnglish title 2-((6-Chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrileChinese alias alogliptin-B | 2-[(6-Chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]benzonitrile | Alogliptin intermediate | Alogliptin benzoate intermediate 1English aliases morePhysicochemical propertiesDensity 1.4±0.1 g/cm3boiling factor 418.0±55.0 °C at 760 mmHgMolecular formulation C13H10ClN3O2Molecular Weight: 275.690flash factor 206.6±31.5 °CExact
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CAS 39263-32-6 Purity 98%Molecular weight 197.04 Molecular formula C7H5BrN2Leadtime In stock Size gItem No. 1031675 Application Chemical, bioindustry, pharmaceuticalFor more product specifications, please consult customer service; Product Name: 2-Amino-5-bromobenzonitrile_Leyan reagent; CAS:39263-32-6; Molecular Formula: C7H5BrN2; Molecular weight: 197.04; storage conditions: 2-8 °C, protect from light2-Amino-5-bromobenzonitrileCAS No.
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Cloxazon, chemical identify 5-chloro-2-benzoxazolidone, molecular system C7H4ClNO2, is a muscle relaxant appearing on the center, used for more than a few acute and persistent smooth tissue (muscle, ligament) sprains, contusions, muscle aches after exercise, muscle spasms brought on through central neuropathy and continual fasciitis.【Chinese alias】Muscle relaxant; Chlordobenazole; 5-Chloro-2-hydroxybenzoxazole; Chloroxazolone; Chlordobenazole; Chlordobenazole; 5-Chloro-2-benzoxazolinone; 5-Chloro-2-benzoxazolone; 6
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CAS1563-56-0InchiInChI=1S/C12H9BrN2O/c13-8-4-5-10(14)9(7-8)12(16)11-3-1-2-6-15-11/h1-7H,14H2InChIkeyKHVZPFKJBLTYCC-UHFFFAOYSA-NChinese aliasBromazepam Impurity A Bromazepam Impurity A(EP) Standard 2-Amino-5-bromophenyl-2-pyridylmethanone 2-(2-amino-5-bromobenzoyl)pyridineCanonical SmilesC1=CC=NC(=C1)C(=O)C2=C(C=CC(=C2)Br)NInternationalization joint naming(2-amino-5-bromophenyl)-pyridin-2-ylmethanoneEnglish alias2-(5-Bromo-2-aminobenzoyl)pyridine(2-Amino-5-bromophenyl)-2-pyridinylmethanone2-(2-Amino-5-bromobenzoyl)pyridineKetone, 2-amino-5-bromophenyl 2-pyridyl2-Amino-5-bromophenyl-2-pyridylmet
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Chinese aliasBromazepam Impurity A Bromazepam Impurity A(EP) Standard 2-Amino-5-bromophenyl-2-pyridylmethanone 2-(2-amino-5-bromobenzoyl)pyridineEnglish alias2-(5-Bromo-2-aminobenzoyl)pyridine(2-Amino-5-bromophenyl)-2-pyridinylmethanone2-(2-Amino-5-bromobenzoyl)pyridineKetone, 2-amino-5-bromophenyl 2-pyridyl2-Amino-5-bromophenyl-2-pyridylmethanone2-Amino-5-bromophenyl 2-pyridyl ketone(2-amino-5-bromophenyl)-pyridin-2-ylmethanone2-(2-AMINO-5-BROMOBENZOYL) PYRIDINE4-bromo-2-[(pyridin-2-yl)carbonyl]anilineMethanone, (2-amino-5-bromophenyl)-2-pyridinyl-(2-Amino-5-bromophenyl)(2-pyridinyl)met
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Molecular shape dataMolar refractive index: 41.72Molar extent (cm3/mol): 128.4Isotonic unique quantity (90.2K): 338.5Surface tension (dyne/cm): 48.2Polarizability (10-24cm3): 16.54Computational chemical dataHydrophobic parameters calculation reference price (XlogP): 1.7Number of hydrogen bonded donors: 1Number of hydrogen bond receptors: threeNumber of rotatable chemical bonds: 1Number of tautomers:Topological molecular polar floor place (TPSA): 54.4Number of heavy atoms: elevenSurface charge: zeroComplexity:
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Cloxazon, chemical name 5-chloro-2-benzoxazolidone, molecular formula C7H4ClNO2, is a muscle relaxant acting on the center, used for various acute and chronic soft tissue (muscle, ligament) sprains, contusions, muscle aches after exercise, muscle spasms caused by central neuropathy and chronic fasciitis.【Chinese alias】Muscle relaxant; Chlordobenazole; 5-Chloro-2-hydroxybenzoxazole; Chloroxazolone; Chlordobenazole; Chlordobenazole; 5-Chloro-2-benzoxazolinone; 5-Chloro-2-benzoxazolone; 6-Chlorobenzoxazolone.【Molecular Formula】C7H4ClNO2 【Molecular Weight】169.57 【CAS】95-25-0【Usage and dosage】Oral:
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CAS:21739-92-4Product Category: Chemical Intermediates - Other Intermediates Cas Number: 21739-92-4Product Specifications: 99% Packing: 25 kg Brand: Runde Detailed Description:5-Bromo-2-chlorobenzoic acidChinese synonyms: 2-Chloro-5-bromobenzoic acid; 5-Bromo-2-chlorobenzoic acid; 5-Bromo-2-chlorobenzoic acid; 5-BroMo-2-chlorobenzoic acid, 98+%; 5-Bromo-2-chlorobenzoic acid; 2-Chloro-5-bromobenzoic acid, 99.86%; 5-Bromo-2-chlorobenzoic acid/2-chloro-5-bromobenzoic acid; 5-BroMo-2-chlorobenzoic acid, 98+%Name: 5-Bromo-2-chlorobenzoic acidEnglish synonyms:Benzoic acid, 5-bromo-2-chloro-; 2-CHLOR
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Pharmacology and toxicologyThis product is an amide local anesthetic. After blood absorption or intravenous administration, it has obvious excitation and inhibition biphasic effect on the central nervous system, and there can be no precursor excitement, when the blood concentration is low, analgesia and drowsiness, and the pain threshold is increased; With the increase of dose, the effect or toxicity increases, and there is an anticonvulsant effect at the concentration of subtoxic blood drugs; When the blood concentration exceeds 5 mg·mL-1, convulsions can occur.
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Pharmacology and toxicologyWhen the plasma concentration exceeds 5 μg·mL-1, convulsions can occur, and at low doses, it can promote the outflow of K+ in myocardial cells, reduce the auto-discipline of the myocardium, and have anti-ventricular arrhythmic effect; At therapeutic doses, there is no significant effect on the electrical activity of cardiomyocytes, atrioventricular conduction and contraction of myocardium; Further increase in blood concentration can cause slowing of cardiac conduction velocity, atrioventricular block, inhibition of myocardial contractility and decrease of cardiac out
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English alias(S)-Methyl 3-(7-bromo-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanoate1H-1,4-Benzodiazepine-3-propanoic acid, 7-bromo-2,3-dihydro-2-oxo-5-(2- pyridinyl)-, methyl ester, (3S)-(3S)-(7-BroMo-2-oxo-5-pyridin-2-yl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-propionic acid Methyl esterMethyl 3-[(3S)-7-bromo-2-oxo-5-(2- pyridinyl)-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanoateCAS308242-23-1InchiInChI=1S/C18H16BrN3O3/c1-25-16(23)8-7-15-18(24)22-13-6-5-11(19)10-12(13)17(21-15)14-4-2-3-9-20-14/h2-6,9-10,15H,7-8H2,1H3,(H,22,24)/t15-/m0/s1InChIkeyPITXBYGUVDYTBQ-HNN
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Chemical composition informationINCI: 1,2-Hexanediol (1,2-Hexanediol)CAS No.:6920-22-5Molecular formula: C₆ H₁₄ O₂Molecular weight: 118.18g/molSpecific parametersAppearance: colorless obvious liquidOdor: totally odorlessPurity: >99.8%Water content: <0.2%Relative density (20°C): 0.946-0.956 g/cmRefractive index (25°C): 1.437-1.447pH (25°C): 6.5±0.5Boiling point: 223-224°C (at 760.00mm Hg)Air pressure: 9mbar (at 108°C)Flash point: 122°CMelting point: forty five °cStorage: Sealed storage in a cool location away from mild and keep away f
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